Bis(2-furyl)chlorophosphine CAS 181257-35-2

Purity 97%+In StockPharmaceutical Standards
CAS No.181257-35-2
Molecular FormulaC8H6ClO2P
Molecular Weight200.56 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

Bis(2-furyl)chlorophosphine CAS 181257-35-2 chemical structure

Description

Compared with other compounds in its class, the molecular weight of 200.56 g/mol gives Bis(2-furyl)chlorophosphine distinctive chromatographic separation conditions and mass-spectrometry parameter settings.

Bis(2-furyl)chlorophosphine (CAS 181257-35-2), molecular formula C8H6ClO2P and molecular weight 200.56 g/mol, is a CATO reference standard with documented purity and traceability.

The molecular framework of Bis(2-furyl)chlorophosphine (C8H6ClO2P) is characterized by organophosphorus functionality, a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by the polarity and ionization state of its functional groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

Molecular FormulaC8H6ClO2P
Molecular Weight200.56 g/mol
AppearanceOff-white to pale yellow crystalline powder. (slight halide-like odor)
Purity97%+
StorageStore at room temperature, keep tightly closed to prevent evaporation
Solubility (reference)Soluble in methanol, acetonitrile, DMSO, water (slightly soluble)
StabilityMay oxidize slowly on prolonged air exposure; Contains ester bond; hydrolyzes under strong alkaline conditions
Degree of Unsaturation (DBE)5.5
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)2008
Halogen ContentCl-containing

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Why CATO?