Picosulfate impurity 20 CAS 181423-88-1
| CAS No. | 181423-88-1 |
| Molecular Formula | C18H13NO2 |
| Molecular Weight | 275.30 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Picosulfate impurity 20 (C18H13NO2) contains a steroid core, an amide group, a hydroxyl group, an ether linkage. Its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
CATO supplies Picosulfate impurity 20 (CAS 181423-88-1), a pharmacopoeial impurity reference standard (molecular formula C18H13NO2, MW 275.30 g/mol) used for the identification and quantification of trace impurities in APIs.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C18H13NO2 |
| Molecular Weight | 275.30 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 13.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2008 |
| Nitrogen Atoms | 1 |
Related Picosulfate Standards
- Picosulfate Impurity 12 (CAS 105745-58-2)
- Picosulfate Impurity 15 (CAS 16985-07-2)
- Picosulfate Impurity 16 (CAS 13004-51-8)
- Picosulfate Impurity 17 (CAS 109810-81-3)
- Sodium Picosulfate EP Impurity B (CAS 603-41-8)
- Picosulfate Impurity 4 (CAS CATO-C4X-12374)
- Sodium Picosulfate Impurity 9 (CAS 2379877-99-1)
- Picosulfate impurity 21 (CAS CATO-C4X-123721)
Recommended Standards
- Ramosetron Impurity 13 (CAS 183613-77-6)
- Levosimendan impurity 74 (CAS CATO-C4X-130874)
- Arbidol Impurity 13 (CAS 40945-79-7)
- Levosimendan Impurity 81 (CAS CATO-C4X-130881)
- Rimegepant Impurity 125 (CAS CATO-C4X-2487125)
- Ceritinib Impurity 17 (CAS CATO-C4X-1048917)
- Icaritin Impurity 3 (CAS CATO-C4X-27643)
- Tert-butyl (2R,3S)-3-hydroxy-2-phenylpiperidine-1-carboxylate (CAS 763105-93-7)
- 2-Hydroxyhexanenitrile (CAS 64350-07-8)
- Cetilistat (CAS 282526-98-1)
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- Methyl 1-(2,4-dichlorophenyl)-4-hydroxy-6-oxo-1,6-dihydropyridazine-3-carboxylate (CAS 121582-57-8)
- 1-(2,4-Dichlorophenyl)-2-((5-phenyl-1,3,4-oxadiazol-2-yl)thio)ethan-1-one (CAS 477846-68-7)
- Copper Peptide ·2 acetate salt (CAS 130120-57-9)
Why CATO?
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- 130,000+ catalog items in stock, COA supplied with every batch
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- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com