Artemisinin Impurity 4 CAS 181528-64-3
| CAS No. | 181528-64-3 |
| Molecular Formula | C16H26O5 |
| Molecular Weight | 298.37 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of Artemisinin Impurity 4 (C16H26O5) is characterized by a carboxylic acid group, a hydroxyl group, an ether linkage, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by the polarity and ionization state of its functional groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Artemisinin Impurity 4 (CAS 181528-64-3) is a certified pharmaceutical impurity reference standard with the molecular formula C16H26O5 and a molecular weight of 298.37 g/mol.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
CATO manufactures Artemisinin Impurity 4 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C16H26O5 |
| Molecular Weight | 298.37 g/mol |
| Appearance | Off-white to pale yellow crystalline powder |
| Purity | >95% |
| Storage | Store at room temperature, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2008 |
Related Artemisinin Standards
- Artemisinin Impurity 2 (CAS 1453465-55-8)
- Artemisinin-d3 (CAS 176652-07-6)
- Artemisinin Impurity 11 (CAS 81496-81-3)
- 9-epi-Artemisinin (CAS 113472-97-2)
- Artemisinin (CAS 63968-64-9)
- Artemisinin Impurity 17 (CAS CATO-C4X-201217)
- Artemisinin Impurity 9 (CAS CATO-C4X-20129)
- Artemisinin Impurity 10 (CAS 2989438-72-2)
Recommended Standards
- Artemether (CAS 71963-77-4)
- Canagliflozin Impurity 4 (CAS CATO-C4X-11234)
- Mono(2-ethyl-5-hydroxyhexyl) Phthalate-d4 (CAS 679789-43-6)
- (2S)-7-hydroxy-2-(4-hydroxyphenyl)-5-methoxy-chroman-4-one 61775-19-7 CTK2F6812 (CAS 61775-19-7)
- Orlistat Impurity 25 (CAS CATO-C4X-149925)
- Carboplatin Impurity 12 (CAS 113287-15-3)
- Gefitinib Impurity 76 (CAS CATO-C4X-111776)
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- 5-Methoxy-3,6-dimethylpyrazin-2-ol (CAS 100868-54-0)
- Liraglutide-d8 Tetratrifluoroacetate (CAS 204656-20-2 (non-labelled, free base))
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com