6-Bromo-8-fluoro-[1,2,4]triazolo[4,3-a]pyridin-3(2H)-one CAS 1816253-36-7

Purity 97%+In StockPharmaceutical Standards
CAS No.1816253-36-7
Molecular FormulaC6H3BrFN3O
Molecular Weight232.01 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

6-Bromo-8-fluoro-[1,2,4]triazolo[4,3-a]pyridin-3(2H)-one CAS 1816253-36-7 chemical structure

Description

Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 6-Bromo-8-fluoro-[1,2,4]triazolo[4,3-a]pyridin-3(2H)-one.

6-Bromo-8-fluoro-[1,2,4]triazolo[4,3-a]pyridin-3(2H)-one (CAS 1816253-36-7), molecular formula C6H3BrFN3O and molecular weight 232.01 g/mol, is a CATO reference standard with documented purity and traceability.

6-Bromo-8-fluoro-[1,2,4]triazolo[4,3-a]pyridin-3(2H)-one (C6H3BrFN3O) contains an amide group, a hydroxyl group, an ether linkage, fluorine/bromine substitution, an aromatic ring system. Halogen substitution raises its density and boiling point; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

As a certified reference material (CRM), 6-Bromo-8-fluoro-[1,2,4]triazolo[4,3-a]pyridin-3(2H)-one meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

Molecular FormulaC6H3BrFN3O
Molecular Weight232.01 g/mol
AppearanceOff-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility)
Purity97%+
StorageStore at 2-8°C, protect from light, keep tightly closed to prevent evaporation
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light
Degree of Unsaturation (DBE)6.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1995
Halogen ContentF/Br-containing
Nitrogen Atoms3

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