tert-Butyl trans-3-(hydroxymethyl)-4-(trifluoromethyl)pyrrolidine-1-carboxylate CAS 1817633-15-0
| CAS No. | 1817633-15-0 |
| Molecular Formula | C11H18F3NO3 |
| Molecular Weight | 269.26 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of tert-Butyl trans-3-(hydroxymethyl)-4-(trifluoromethyl)pyrrolidine-1-carboxylate (C11H18F3NO3) is characterized by an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
CATO supplies tert-Butyl trans-3-(hydroxymethyl)-4-(trifluoromethyl)pyrrolidine-1-carboxylate (CAS 1817633-15-0), a certified reference material (molecular formula C11H18F3NO3, MW 269.26 g/mol) for analytical method development and quality control.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO manufactures tert-Butyl trans-3-(hydroxymethyl)-4-(trifluoromethyl)pyrrolidine-1-carboxylate under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C11H18F3NO3 |
| Molecular Weight | 269.26 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 2.0 |
| CAS Registry Year (est.) | 1995 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Recommended Standards
- 3-{1-methyl-2-oxo-1H,2H,3H-imidazo[4,5-b]pyridin-6-yl}benzoic acid (CAS 1797210-14-0)
- Tert-butyl 3-hydroxy-5-(trifluoromethyl)piperidine-1-carboxylate (CAS 1824210-98-1)
- tert-Butyl 4-hydroxy-2-(trifluoromethyl)piperidine-1-carboxylate (CAS 1785759-35-4)
- Tert-butyl 2-((S)-2,2,2-trifluoro-1-hydroxyethyl)pyrrolidine-1-carboxylate (CAS 1888470-07-2)
- 5-(4-Acetylphenyl)-2-furaldehyde (CAS 57268-39-0)
- 3-[(Phenylsulfonyl)methyl]piperidine hydrochloride (CAS 101768-74-5)
- Methyl (2r,3s)-2-(4-methoxyphenyl)pyrrolidine-3-carboxylate (CAS 748777-12-0)
- <SC>D</SC>-Proline-1-<SUP>13</SUP>C (CAS 1202064-03-6)
- {[3-(1-ethoxyethyl)-1,2,4-oxadiazol-5-yl]methyl}(methyl)amine (CAS 1338942-95-2)
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- tert-Butyl 4-bromo-3-(hydroxymethyl)-1H-indole-1-carboxylate (CAS 914349-05-6)
- Biotinyl-Pancreatic Polypeptide (human) trifluoroacetate salt (CAS 1816258-36-2)
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