(Z)-5-(4-iodobenzylidene)-2-thioxothiazolidin-4-one CAS 181765-52-6

Description

Compared with other compounds in its class, the molecular weight of 347.20 g/mol gives (Z)-5-(4-iodobenzylidene)-2-thioxothiazolidin-4-one distinctive chromatographic separation conditions and mass-spectrometry parameter settings.

(Z)-5-(4-iodobenzylidene)-2-thioxothiazolidin-4-one (CAS 181765-52-6) is a high-purity analytical reference standard with the molecular formula C10H6INOS2 and a molecular weight of 347.20 g/mol.

The molecular framework of (Z)-5-(4-iodobenzylidene)-2-thioxothiazolidin-4-one (C10H6INOS2) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, sulfur-containing functionality, a hydroxyl group, an ether linkage, iodine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

As a certified reference material (CRM), (Z)-5-(4-iodobenzylidene)-2-thioxothiazolidin-4-one meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

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