(Z)-5-((1H-Indol-3-yl)methylene)-2-thioxothiazolidin-4-one CAS 181765-59-3

Description

Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including (Z)-5-((1H-Indol-3-yl)methylene)-2-thioxothiazolidin-4-one.

(Z)-5-((1H-Indol-3-yl)methylene)-2-thioxothiazolidin-4-one (CAS 181765-59-3), molecular formula C12H8N2OS2 and molecular weight 260.33 g/mol, is a CATO reference standard with documented purity and traceability.

Based on its molecular formula C12H8N2OS2, (Z)-5-((1H-Indol-3-yl)methylene)-2-thioxothiazolidin-4-one contains a nitrogen-containing heterocyclic scaffold, an amide group, sulfur-containing functionality, a hydroxyl group, an ether linkage; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 260.33 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

As a certified reference material (CRM), (Z)-5-((1H-Indol-3-yl)methylene)-2-thioxothiazolidin-4-one meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

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