4-(4-Methylpiperazin-1-yl)-2-phenylquinoline CAS 181775-68-8
| CAS No. | 181775-68-8 |
| Molecular Formula | C20H21N3 |
| Molecular Weight | 303.40 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
4-(4-Methylpiperazin-1-yl)-2-phenylquinoline (CAS 181775-68-8) is a high-purity analytical reference standard with the molecular formula C20H21N3 and a molecular weight of 303.40 g/mol.
Structurally, 4-(4-Methylpiperazin-1-yl)-2-phenylquinoline (C20H21N3) contains a nitrogen-containing heterocyclic scaffold, a nitrile group. The molecule exhibits a degree of unsaturation (DBE) of 12.0, corresponding to approximately 12 ring(s) or double-bond equivalent(s). With a molecular weight of 303.40 g/mol, it falls into the moderately-high-molecular-weight range. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C20H21N3 |
| Molecular Weight | 303.40 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2008 |
| Nitrogen Atoms | 3 |
Related Methylpiperazin Standards
- 2-[4-(4-Methylpiperazin-1-yl)phenyl]quinoline (CAS 861206-59-9)
- 4-(2-(4-Methylpiperazin-1-yl)thiazol-4-yl)benzoic acid (CAS 294622-47-2)
- 2-(4-Methylpiperazin-1-yl)-6-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyrazine (CAS 1186042-00-1)
- 2-(4-Methylpiperazin-1-yl)-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyrimidine (CAS 942922-07-8)
- 1-(2-(6-(4-Methylpiperazin-1-yl)pyridin-3-yl)piperidin-1-yl)ethanone (CAS 1352539-50-4)
- 1-(2-(2-(4-Methylpiperazin-1-yl)pyridin-3-yl)piperidin-1-yl)ethanone (CAS 1352539-85-5)
- 4-(4-Methylpiperazin-1-yl)-2-(pyridin-3-yl)quinoline (CAS 133671-62-2)
- 4-(4-Methylpiperazin-1-yl)-2-phenylquinazoline (CAS 143871-26-5)
Recommended Standards
- 2-(Diphenylphosphanyl)-N-(2-(methylthio)ethyl)ethan-1-amine (CAS 1802182-42-8)
- Tert-butyl 3-hydroxy-2,3-dihydrospiro[indene-1,4'-piperidine]-1'-carboxylate (CAS 185525-42-2)
- N-(Furan-3-ylmethyl)-N-(thiophen-2-ylmethyl)thiophene-2-carboxamide (CAS 1798023-93-4)
- N,N-Dibenzyl-4-methoxyaniline (CAS 18613-55-3)
- 3-(4-Bromophenyl)-5-(((6-(4-isopropylphenyl)pyridazin-3-yl)thio)methyl)-1,2,4-oxadiazole (CAS 1115285-89-6)
- 4-(2-Chlorophenyl)-6-methylthieno[2,3-d]pyrimidin-2(1H)-one (CAS 677713-46-1)
- 4-Fluoro-2,6-dimethylbenzaldehyde (CAS 925441-35-6)
- 5-Chloroquinolin-8-amine (CAS 5432-09-7)
- (6-Methoxy-3-methylbenzofuran-2-yl)(4-methylpiperazin-1-yl)methanone hydrochloride (CAS 35689-00-0)
- Ribociclib N,N-DiDesmethyl Metabolite (CAS CATO-C4X-310038)
- (1S)-Dicyclohexyl(2',6'-dimethoxy-[1,1'-biphenyl]-2-yl)phosphine (CAS 1356823-31-8)
- 5-(8-Chloroisoquinolin-3-yl)-N-methylpicolinamide (CAS 2197909-45-6)
- n-(Heptan-3-yl)-1-methylpyrrolidin-3-amine (CAS 1340567-67-0)
- C-Peptide 1 (rat) (CAS 41475-27-8)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com