(R)-1-(3-Chloro-5-fluorophenyl)ethan-1-amine hydrochloride CAS 1820574-01-3
| CAS No. | 1820574-01-3 |
| Molecular Formula | C8H9ClFN |
| Molecular Weight | N/A |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including (R)-1-(3-Chloro-5-fluorophenyl)ethan-1-amine hydrochloride.
(R)-1-(3-Chloro-5-fluorophenyl)ethan-1-amine hydrochloride (CAS 1820574-01-3) is a high-purity analytical reference standard with the molecular formula C8H9ClFNHCl and a molecular weight of 210.07 g/mol.
(R)-1-(3-Chloro-5-fluorophenyl)ethan-1-amine hydrochloride (C8H9ClFNHCl) contains a nitrile group, fluorine/chlorine substitution. Halogen substitution raises its density and boiling point; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures (R)-1-(3-Chloro-5-fluorophenyl)ethan-1-amine hydrochloride under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C8H9ClFN HCl |
| Molecular Weight | 210.07 g/mol |
| Appearance | White to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 3.0 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 1995 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 1 |
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Recommended Standards
- (4,6-Dichloropyrimidin-5-yl)(2-methylpyridin-3-yl)methanone (CAS 1416373-37-9)
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- CAS CATO-C3D-262898 (CAS CATO-C3D-262898)
- Brensocatib (CAS 1802148-05-5)
- N-methyl-2-(m-tolyloxy)ethan-1-amine (CAS 200350-18-1)
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