(3R,4S)-4-(p-Tolyl)pyrrolidine-3-carboxylic acid hydrochloride CAS 1820580-69-5
| CAS No. | 1820580-69-5 |
| Molecular Formula | C12H15NO2 |
| Molecular Weight | N/A |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
CATO supplies (3R,4S)-4-(p-Tolyl)pyrrolidine-3-carboxylic acid hydrochloride (CAS 1820580-69-5), a certified reference material (molecular formula C12H15NO2HCl, MW 241.72 g/mol) for analytical method development and quality control.
The molecular framework of (3R,4S)-4-(p-Tolyl)pyrrolidine-3-carboxylic acid hydrochloride (C12H15NO2HCl) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures (3R,4S)-4-(p-Tolyl)pyrrolidine-3-carboxylic acid hydrochloride under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C12H15NO2 HCl |
| Molecular Weight | 241.72 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1995 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
Recommended Standards
- N-(2-Fluorophenyl)-3-(2-methoxyphenyl)-2-(2H-1,2,3,4-tetrazol-5-yl)propanamide (CAS 483993-72-2)
- Benzyl (5-fluoroazepan-4-yl)carbamate hydrochloride (CAS 1823835-61-5)
- Methyl 1-(1,3-benzoxazol-2-yl)piperidine-4-carboxylate (CAS 1090401-36-7)
- Fesoterodine Related Impurity 11 (CAS 194482-42-3)
- 3-Chloro-4-(chloromethyl)-5-(difluoromethyl)pyridin-2-amine (CAS 1806831-31-1)
- (2R,3R)-2-(4-chlorophenyl)-4,4,4-trifluoro-3-methylbutanoic acid (CAS 1402937-46-5)
- 3-(4-Fluorophenoxy)benzaldehyde (CAS 65295-61-6)
- tert-Butyl 6-(difluoromethyl)-8-hydroxy-3,4-dihydroisoquinoline-2(1H)-carboxylate (CAS 2159120-76-8)
- Ethyl 2-(5-bromo-2-cyano-3-(trifluoromethyl)phenyl)acetate (CAS 1805188-29-7)
- Semaglutide impurity 205 (CAS CATO-C4X-2226205)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com