(2R,3R)-3-(chloromethyl)-2-(4-(trifluoromethyl)phenyl)tetrahydro-2H-pyran CAS 1820583-14-9
| CAS No. | 1820583-14-9 |
| Molecular Formula | C13H14ClF3O |
| Molecular Weight | 278.70 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of (2R,3R)-3-(chloromethyl)-2-(4-(trifluoromethyl)phenyl)tetrahydro-2H-pyran is closely related to a hydroxyl group, an ether linkage, fluorine/chlorine substitution, an aromatic ring system in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
(2R,3R)-3-(chloromethyl)-2-(4-(trifluoromethyl)phenyl)tetrahydro-2H-pyran (CAS 1820583-14-9) is a high-purity analytical reference standard with the molecular formula C13H14ClF3O and a molecular weight of 278.70 g/mol.
Structurally, (2R,3R)-3-(chloromethyl)-2-(4-(trifluoromethyl)phenyl)tetrahydro-2H-pyran (C13H14ClF3O) contains a hydroxyl group, an ether linkage, fluorine/chlorine substitution, an aromatic ring system. The molecule exhibits a degree of unsaturation (DBE) of 5.0, corresponding to approximately 5 ring(s) or double-bond equivalent(s). With a molecular weight of 278.70 g/mol, it falls into the medium-molecular-weight range. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), (2R,3R)-3-(chloromethyl)-2-(4-(trifluoromethyl)phenyl)tetrahydro-2H-pyran meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C13H14ClF3O |
| Molecular Weight | 278.70 g/mol |
| Purity | 97%+ |
| Storage | Store at room temperature, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1995 |
| Halogen Content | F/Cl-containing |
Recommended Standards
- 3-(Chloromethyl)-2-(4-(trifluoromethyl)phenyl)tetrahydro-2H-pyran (CAS 1522221-98-2)
- 6-Chloro-1-oxo-1-(3-trifluoromethylphenyl)hexane (CAS 898783-58-9)
- 3-Chloro-2-(3-methyl-1-piperidinyl)-5-(trifluoromethyl)pyridine (CAS 1220036-31-6)
- 6-Chloro-1-oxo-1-(4-trifluoromethylphenyl)hexane (CAS 890043-20-6)
- Methyl (2-nitrobenzyl)carbamic acid tert-butyl ester, 97% (CAS 868783-62-4)
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- (S)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-4-methyl-4-phenylpentanoic acid (CAS 2350186-20-6)
- 5-(3-Methylpiperidin-1-yl)-1,3,4-thiadiazol-2-amine (CAS 941867-25-0)
- (R)-tert-Butyl 5-methyl-4-((R)-1-methyl-2-oxo-1,2,3,5-tetrahydrobenzo[5,6][1,4]oxazino[3,4-c][1,2,4]triazin-9-yl)-5,6-dihydropyridine-1(2H)-carboxylate (CAS 1613722-44-3)
- Peptide Impurity 24 (CAS CATO-CPTD788824)
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