3-Bromo-5-fluoro-1-methyl-1H-pyrazole CAS 1820608-53-4
| CAS No. | 1820608-53-4 |
| Molecular Formula | C4H4BrFN2 |
| Molecular Weight | 178.99 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
3-Bromo-5-fluoro-1-methyl-1H-pyrazole (CAS 1820608-53-4), molecular formula C4H4BrFN2 and molecular weight 178.99 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 3-Bromo-5-fluoro-1-methyl-1H-pyrazole (C4H4BrFN2) is characterized by a nitrile group, fluorine/bromine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 3-Bromo-5-fluoro-1-methyl-1H-pyrazole under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C4H4BrFN2 |
| Molecular Weight | 178.99 g/mol |
| Appearance | White to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 3.0 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 1995 |
| Halogen Content | F/Br-containing |
| Nitrogen Atoms | 2 |
Related Bromo Standards
- 4-Bromo-1-(fluoromethyl)-1H-pyrazole (CAS 1224194-56-2)
- 5-bromo-3-fluoro-1-methyl-pyrazole (CAS 1780764-54-6)
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- 5-Bromo-4-fluoro-1-methyl-1H-imidazole (CAS 1823245-72-2)
- 5-Bromo-4-fluoro-1-methyl-1h-pyrazole (CAS 1935264-08-6)
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Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
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