Methyl 4-(3,4-difluorophenyl)-2-fluorobenzoate CAS 1820640-08-1
| CAS No. | 1820640-08-1 |
| Molecular Formula | C14H9F3O2 |
| Molecular Weight | 266.22 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Methyl 4-(3,4-difluorophenyl)-2-fluorobenzoate.
CATO supplies Methyl 4-(3,4-difluorophenyl)-2-fluorobenzoate (CAS 1820640-08-1), a certified reference material (molecular formula C14H9F3O2, MW 266.22 g/mol) for analytical method development and quality control.
Structurally, Methyl 4-(3,4-difluorophenyl)-2-fluorobenzoate (C14H9F3O2) contains a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution, a polycyclic aromatic system. The molecule exhibits a degree of unsaturation (DBE) of 9.0, corresponding to approximately 9 ring(s) or double-bond equivalent(s). With a molecular weight of 266.22 g/mol, it falls into the medium-molecular-weight range. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures Methyl 4-(3,4-difluorophenyl)-2-fluorobenzoate under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C14H9F3O2 |
| Molecular Weight | 266.22 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1995 |
| Halogen Content | F-containing |
Related Methyl Standards
- (2,4-Difluorophenyl)(3-fluoro-4-methoxyphenyl)methanone (CAS 1154186-23-8)
- Methyl 4-(2,5-difluorophenyl)-2-fluorobenzoate (CAS 1820639-84-6)
- Methyl 4-(3,5-difluorophenyl)-3-fluorobenzoate (CAS 1820711-01-0)
- (3,5-Difluorophenyl)(3-fluoro-4-methoxyphenyl)methanone (CAS 844885-14-9)
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Recommended Standards
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- 2'-(Trifluoromethyl)-[1,1'-biphenyl]-3-carboxylic acid (CAS 168618-48-2)
- 4-(Trifluoromethyl)-[1,1'-biphenyl]-2-carboxylic acid (CAS 182439-39-0)
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- 81988-89-8 UH11FDQ454 Ramoplanin A(sub 3) Ramoplanin A3 (S)-2-(3-Chloro-4-hydroxyphenyl)-N-(N(sup 2)-((2Z,4Z)-8-methyl-2,4-nonadienoyl)-(S)-asparaginyl-(2S,3S)-3-hydroxyasparaginyl-(R)-2-(p-hydroxyphenyl)glycyl-(R)-ornithyl-(2R,3R)-allothreonyl-2-(p-hydroxyphenyl)glycyl-2-(p-hydroxyphenyl)glycyl-(2S,3S)-allothreonyl-(S)-phenylalanyl-(R)-ornithyl-(S)-2-(p-((2-O-alpha-D-mannopyranosyl-alpha-D-mannopyranosyl)oxy)phenyl)glycyl-(2R,3R)-allothreonyl-(S)-2-(p-hydroxyphenyl)glycylglycyl-(S)-leucyl-(R)-alanyl)glycine psi1-lactone Ramoplanin A 1 (peptide moiety), 1-(N(sup 2)-methyl-1-oxo-2,4-nonadienyl)-L-asparagine)-11-(L-2-(4-((2-O-alpha-D-mannopyranosyl-alpha-D-mannopyranosyl)oxy)phenyl)glycine)-, (Z,Z)- UNII-UH11FDQ454 (CAS 81988-89-8)
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