Methyl 4-(2,4-dimethoxyphenyl)-2-fluorobenzoate CAS 1820648-16-5
| CAS No. | 1820648-16-5 |
| Molecular Formula | C16H15FO4 |
| Molecular Weight | 290.29 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Methyl 4-(2,4-dimethoxyphenyl)-2-fluorobenzoate (CAS 1820648-16-5) is a high-purity analytical reference standard with the molecular formula C16H15FO4 and a molecular weight of 290.29 g/mol.
The molecular framework of Methyl 4-(2,4-dimethoxyphenyl)-2-fluorobenzoate (C16H15FO4) is characterized by a flavonoid core, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), Methyl 4-(2,4-dimethoxyphenyl)-2-fluorobenzoate meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C16H15FO4 |
| Molecular Weight | 290.29 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1995 |
| Halogen Content | F-containing |
Related Methyl Standards
- Methyl 4-(3,5-dimethoxyphenyl)-2-fluorobenzoate (CAS 1820711-12-3)
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Recommended Standards
- 2-(3-(4-Fluorophenyl)-2-oxo-1,4-diazaspiro[4.4]non-3-en-1-yl)acetic acid (CAS 1708080-16-3)
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- 2-Hydroxy-n-(2-hydroxyethyl)-s-(4-nitrophenyl)ethane-1-sulfonamido (CAS 18226-07-8)
- Methyl 3-amino-5-nitrobenzoate hydrochloride (CAS 178906-99-5)
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