1-Bromo-2-chloro-4-fluoro-3-iodobenzene CAS 1820649-92-0
| CAS No. | 1820649-92-0 |
| Molecular Formula | C6H2BrClFI |
| Molecular Weight | 335.34 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 1-Bromo-2-chloro-4-fluoro-3-iodobenzene.
1-Bromo-2-chloro-4-fluoro-3-iodobenzene (CAS 1820649-92-0), molecular formula C6H2BrClFI and molecular weight 335.34 g/mol, is a CATO reference standard with documented purity and traceability.
Owing to fluorine/chlorine/bromine/iodine substitution, an aromatic ring system, 1-Bromo-2-chloro-4-fluoro-3-iodobenzene is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 335.34 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 1-Bromo-2-chloro-4-fluoro-3-iodobenzene under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C6H2BrClFI |
| Molecular Weight | 335.34 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at room temperature |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO |
| Stability | May oxidize slowly on prolonged air exposure |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1995 |
| Halogen Content | F/Cl/Br/I-containing |
Related Bromo Standards
- 4-Bromo-2-chloro-5-fluoroiodobenzene (CAS 1000572-73-5)
- 1-Bromo-2-chloro-3-fluoro-4-iodobenzene (CAS 1000573-03-4)
- 1-Bromo-3-chloro-5-fluoro-2-iodobenzene (CAS 1000577-66-1)
- 1-Bromo-5-chloro-4-fluoro-2-iodobenzene (CAS 1067882-65-8)
- 1-Bromo-2-chloro-5-fluoro-4-iodobenzene (CAS 1160574-56-0)
- 1-Bromo-4-chloro-5-fluoro-2-iodobenzene (CAS 1263377-64-5)
- 1-Bromo-3-chloro-2-fluoro-5-iodobenzene (CAS 1416241-38-7)
- 1-Bromo-4-chloro-2-fluoro-3-iodobenzene (CAS 1820641-80-2)
Recommended Standards
- 1-Bromo-4-chloro-3-fluoro-2-iodobenzene (CAS 1820674-47-2)
- Methyl (4-(trifluoromethyl)benzoyl)-L-methioninate (CAS 175202-25-2)
- 1-Bromo-3-chloro-2-fluoro-4-iodobenzene (CAS 1917307-72-2)
- 2-Bromo-1-chloro-4-fluoro-3-iodobenzene (CAS 1935178-59-8)
- Methyl 2,6-dichloro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzoate (CAS 1321613-04-0)
- 5-Cyclopropyl-4-(1-phenylethyl)-4H-1,2,4-triazole-3-thiol (CAS 893764-69-7)
- N-(1-Methyl-6-phenyl-1H-imidazo[4,5-b]pyridin-2-yl)hydroxylamine (CAS 124489-20-9)
- 2-(Aminomethyl)-4-chloro-3-(difluoromethyl)pyridine-6-methanol (CAS 1805276-94-1)
- Pipemidic Acid Methyl Ester (CAS 80161-83-7)
- Ethyl 6-fluoro-8-methyl-4-(piperazin-1-yl)quinoline-3-carboxylate (CAS 1315345-09-5)
- Amlodipine Impurity 48 (CAS CATO-C4X-109548)
- 2-(((3-Bromobenzyl)oxy)methyl)furan (CAS 1248138-11-5)
- 8-Chloro-[1,2,4]triazolo[1,5-a]pyrazine (CAS 74803-32-0)
- Peptide Impurity 26 (CAS 1350456-66-4)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
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- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com