Methyl 3-[4-(trifluoromethoxy)phenyl]benzoate CAS 1820666-93-0
| CAS No. | 1820666-93-0 |
| Molecular Formula | C15H11F3O3 |
| Molecular Weight | 296.24 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
Methyl 3-[4-(trifluoromethoxy)phenyl]benzoate (CAS 1820666-93-0), molecular formula C15H11F3O3 and molecular weight 296.24 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of Methyl 3-[4-(trifluoromethoxy)phenyl]benzoate (C15H11F3O3) is characterized by a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution, a polycyclic aromatic system. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
CATO manufactures Methyl 3-[4-(trifluoromethoxy)phenyl]benzoate under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C15H11F3O3 |
| Molecular Weight | 296.24 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1995 |
| Halogen Content | F-containing |
Related Methyl Standards
- 2-(4'-(Trifluoromethoxy)-[1,1'-biphenyl]-3-yl)acetic acid (CAS 1224742-16-8)
- Methyl 4-[3-(trifluoromethoxy)phenyl]benzoate (CAS 1433879-01-6)
- 4-((4-(Trifluoromethoxy)phenoxy)methyl)benzaldehyde (CAS 1442084-85-6)
- 3-((4-(Trifluoromethoxy)phenoxy)methyl)benzaldehyde (CAS 1443310-81-3)
- 2-((4-(Trifluoromethoxy)phenoxy)methyl)benzaldehyde (CAS 1443345-70-7)
- Methyl 2-[4-(trifluoromethoxy)phenyl]benzoate (CAS 1528793-38-5)
- Methyl 3-[2-(trifluoromethoxy)phenyl]benzoate (CAS 1820613-75-9)
- Methyl 3-[3-(trifluoromethoxy)phenyl]benzoate (CAS 1820666-90-7)
Recommended Standards
- Methyl 4-[2-(trifluoromethoxy)phenyl]benzoate (CAS 1820716-23-1)
- 2-(Benzyloxy)-4-(trifluoromethyl)benzoic acid (CAS 1822843-97-9)
- 4-Benzyloxy-2-(trifluoromethoxy)benzaldehyde (CAS 1809158-19-7)
- 2-(4-(3-(Trifluoromethoxy)phenyl)pyridin-2-yl)acetamide (CAS 1853166-29-6)
- 2-Chloro-5-fluoro-4-(4-fluoro-2-methoxyphenyl)pyrimidine (CAS 1426215-30-6)
- 1-(5-((9-((2R,4S,5R)-4-Hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-9H-purin-6-yl)amino)-4-methyltetrahydrofuran-3-yl)ethanone (CAS 97994-65-5)
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- 5,5-difluoro-1-oxido-spiro[6H-pyrano[3,4-b]pyridin-1-ium-8,3'-tetrahydrofuran] (CAS 2761389-79-9)
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- T-Peptide (CAS 2022956-62-1)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com