(E)-6-(3-(Dimethylamino)acryloyl)-7-hydroxy-8-methyl-4-propyl-2h-chromen-2-one CAS 1821457-37-7
| CAS No. | 1821457-37-7 |
| Molecular Formula | C18H21NO4 |
| Molecular Weight | 315.36 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including (E)-6-(3-(Dimethylamino)acryloyl)-7-hydroxy-8-methyl-4-propyl-2h-chromen-2-one.
(E)-6-(3-(Dimethylamino)acryloyl)-7-hydroxy-8-methyl-4-propyl-2h-chromen-2-one (CAS 1821457-37-7) is a high-purity analytical reference standard with the molecular formula C18H21NO4 and a molecular weight of 315.36 g/mol.
The molecular framework of (E)-6-(3-(Dimethylamino)acryloyl)-7-hydroxy-8-methyl-4-propyl-2h-chromen-2-one (C18H21NO4) is characterized by a flavonoid core, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO manufactures (E)-6-(3-(Dimethylamino)acryloyl)-7-hydroxy-8-methyl-4-propyl-2h-chromen-2-one under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C18H21NO4 |
| Molecular Weight | 315.36 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1995 |
| Nitrogen Atoms | 1 |
Related E Standards
- (4Z)-4-[1-(Dimethylamino)-2-(morpholin-4-yl)ethylidene]-2-phenyl-4,5-dihydro-1,3-oxazol-5-one (CAS 1164505-85-4)
- N-(4-(Dimethylamino)-2-(piperidin-1-yl)pyrimidin-5-yl)furan-2-carboxamide (CAS 1797622-52-6)
- 1-(4-(Dimethylamino)-2-methoxypyrimidin-5-yl)-3-(2-ethylphenyl)urea (CAS 1798619-93-8)
- (E)-2-((4-(dimethylamino)benzylidene)amino)-5-phenylfuran-3-carbonitrile (CAS 478033-31-7)
- N-(2-((3-(dimethylamino)propyl)carbamoyl)phenyl)furan-2-carboxamide (CAS 947031-82-5)
- Ethyl 4-(dimethylamino)-3-(1H-pyrrol-1-yl)thieno[2,3-b]pyridine-2-carboxylate (CAS 341967-29-1)
- 4-(Dimethylamino)-N-(6-methyl-4,5,6,7-tetrahydrobenzo[d]thiazol-2-yl)benzamide (CAS 441289-52-7)
- N-[3-(Dimethylamino)propyl]-8-methyl-8H-thieno[2,3-b]indole-2-carboxamide (CAS 860611-35-4)
Recommended Standards
- Codeinone Impurity 3 (CAS 1777-89-5)
- Tert-butyl 2',3-dioxo-2,3-dihydrospiro[indene-1,4'-piperidine]-1'-carboxylate (CAS 1823835-30-8)
- 10Alpha-Hydroxycodeine (CAS 16589-96-1)
- Ethyl 2-(Boc-amino)-1-naphthoate (CAS 1824676-62-1)
- methyl 6-(4-fluorophenyl)-3-methylisoxazolo[5,4-b]pyridine-4-carboxylate (CAS 875424-64-9)
- 3-Hydroxy-4-methoxy-mandelic Acid Ethyl Ester (CAS 91971-78-7)
- 5-Amino-2,6-dichloropyrimidine-4-carboxylic acid (CAS 1207176-09-7)
- 2-(3-Chloro-5-(trifluoromethyl)pyridin-2-yl)-2-(thiophen-2-yl)acetonitrile (CAS 338407-61-7)
- 2,2,2-Trifluoro-N-((5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridin-3-yl)methyl)ethanamine hydrochloride (CAS 919347-59-4)
- N-(3-Methoxy-1-(1H-pyrazol-4-yl)propyl)pyridin-2-amine (CAS 1365958-31-1)
- Menaquinone 7-d7 (CAS 1233937-31-9)
- Diisopropyl 3,3-bis(Hydroxymethyl)cyclobutane-1,1-dicarboxylate (CAS 1237542-08-3)
- 7-Ethynylquinoline-3-carboxylic acid (CAS 1416560-88-7)
- Semaglutide impurity 26 (CAS CATO-C4X-222626)
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