1-(((9H-fluoren-9-yl)methoxy)carbonyl)-4-(trifluoromethyl)pyrrolidine-2-carboxylic acid CAS 1822498-26-9
| CAS No. | 1822498-26-9 |
| Molecular Formula | C21H18F3NO4 |
| Molecular Weight | 405.37 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
1-(((9H-fluoren-9-yl)methoxy)carbonyl)-4-(trifluoromethyl)pyrrolidine-2-carboxylic acid (CAS 1822498-26-9) is a high-purity analytical reference standard with the molecular formula C21H18F3NO4 and a molecular weight of 405.37 g/mol.
Owing to a flavonoid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution, 1-(((9H-fluoren-9-yl)methoxy)carbonyl)-4-(trifluoromethyl)pyrrolidine-2-carboxylic acid is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 405.37 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
As a certified reference material (CRM), 1-(((9H-fluoren-9-yl)methoxy)carbonyl)-4-(trifluoromethyl)pyrrolidine-2-carboxylic acid meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C21H18F3NO4 |
| Molecular Weight | 405.37 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1995 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Related H Standards
- 1-((((9H-fluoren-9-yl)methoxy)carbonyl)amino)-3-(trifluoromethyl)cyclobutane-1-carboxylic acid (CAS 2357927-56-9)
- 2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-2-(1-(trifluoromethyl)cyclopropyl)acetic acid (CAS 2137462-64-5)
- 2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-2-(3,5-dihydroxyphenyl)acetic acid (CAS 943036-36-0)
- 3-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-3-(4-fluorophenyl)propanoic acid (CAS 188814-36-0)
- 2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-3-(2-fluorophenyl)propanoic acid (CAS 678991-28-1)
- 2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-3-(3-fluorophenyl)propanoic acid (CAS 201484-79-9)
- 3-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-3-(3-fluorophenyl)propanoic acid (CAS 284492-07-5)
- 2-{[(9H-Fluoren-9-ylmethoxy)carbonyl]amino}-3-(4-fluorophenyl)propanoic acid 264276-42-8 8754AD C24H20FNO4 (CAS 264276-42-8)
Recommended Standards
- (2s,4s)-1-(((9h-Fluoren-9-yl)methoxy)carbonyl)-4-(trifluoromethyl)pyrrolidine-2-carboxylic acid (CAS 1242934-32-2)
- (1-(tert-Butoxycarbonyl)-5-(((tert-butyldimethylsilyl)oxy)methyl)-1H-indol-2-yl)boronic acid (CAS 335649-84-8)
- Diethyl 2-benzamido-4-(2,2,2-trifluoro-1-hydroxyethyl)pentanedioate (CAS 1214827-37-8)
- (1-(tert-butoxycarbonyl)-6-(((tert-butyldimethylsilyl)oxy)methyl)-1H-indol-2-yl)boronic acid (CAS 501364-51-8)
- 2,5-Difluoro-3-nitroanisole (CAS 1803826-15-4)
- 6-Benzyl-2-(5-bromothiophene-2-carboxamido)-4,5,6,7-tetrahydrothieno[2,3-c]pyridine-3-carboxamide hydrochloride (CAS 1216590-51-0)
- Methyl 9-bromo-8-fluoro-4,5-dihydrobenzo[2,3]oxepino[4,5-d]thiazole-2-carboxylate (CAS 1555704-86-3)
- 2-(6-Bromo-5-hydroxypyridin-3-yl)acetic acid (CAS 1805025-14-2)
- 4-(1,3-dithian-2-yl)phenol (CAS 57529-05-2)
- Eptifibatide Impurity 1 (CAS CATO-C4X-23451)
- 4-Bromo-5-chloro-1H-pyrrolo[2,3-b]pyridine (CAS 916176-52-8)
- Tenuazonic Acid Copper Salt (CAS 76569-74-9)
- N-isopropyl-3-methoxycyclobutan-1-amine (CAS 1691179-62-0)
- [Ser39-OH] Tirzepatide (CAS CATO-C4X-324041)
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