Methyl 6-chloro-5-methylpyrazine-2-carboxylate CAS 1822669-47-5
| CAS No. | 1822669-47-5 |
| Molecular Formula | C7H7ClN2O2 |
| Molecular Weight | 186.60 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Methyl 6-chloro-5-methylpyrazine-2-carboxylate (CAS 1822669-47-5) is a high-purity analytical reference standard with the molecular formula C7H7ClN2O2 and a molecular weight of 186.60 g/mol.
The molecular framework of Methyl 6-chloro-5-methylpyrazine-2-carboxylate (C7H7ClN2O2) is characterized by an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C7H7ClN2O2 |
| Molecular Weight | 186.60 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1995 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
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Recommended Standards
- 2-(5-Amino-3-chloropyridin-2-yl)acetic acid (CAS 1807156-94-0)
- N-(5-Chloro-3-hydroxypyridin-2-yl)acetamide (CAS 1823558-07-1)
- 2-(3-Amino-6-chloropyridin-2-yl)acetic acid (CAS 1805558-23-9)
- methyl 5-(chloromethyl)pyrazine-2-carboxylate (CAS 1824324-58-4)
- 2-(2-Fluorophenyl)-4-methyl-3-oxopentanenitrile (CAS 1249577-87-4)
- 1H-pyrrolo[3,2-b]pyridine-3-sulfonyl chloride (CAS 1782733-34-9)
- 4-(Bromomethyl)-3-(difluoromethyl)benzonitrile (CAS 1261566-79-3)
- Methyl 5-(2-fluorophenyl)-2-imino-2,3-dihydrothiazole-4-carboxylate (CAS 886361-38-2)
- Cyclopropylmethyl Acetate (CAS 36982-54-4)
- (4'-(Trifluoromethoxy)-[1,1'-biphenyl]-4-yl)methanamine (CAS 472964-25-3)
- (E)-Thiothixene (CAS 3313-27-7)
- tert-Butyl 2-(4-bromophenyl)-2-oxoacetate (CAS 1279017-84-3)
- 2-(3,5-Dimethyl-1-pyrazolyl)-4-methylphenylboronic Acid (CAS 1287753-41-6)
- Galanin Message Associated Peptide (44-59) amide (CAS 125455-59-6)
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