2-[3-(Piperazine-1-carbonyl)-1H-1,2,4-triazol-1-yl]ethan-1-ol hydrochloride CAS 1822672-44-5
| CAS No. | 1822672-44-5 |
| Molecular Formula | C9H16N5O2 |
| Molecular Weight | N/A |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
2-[3-(Piperazine-1-carbonyl)-1H-1,2,4-triazol-1-yl]ethan-1-ol hydrochloride (CAS 1822672-44-5), molecular formula C9H16N5O2Cl and molecular weight 261.71 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 2-[3-(Piperazine-1-carbonyl)-1H-1,2,4-triazol-1-yl]ethan-1-ol hydrochloride (C9H16N5O2Cl) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C9H16N5O2 Cl |
| Molecular Weight | 261.71 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1995 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 5 |
Related Piperazine Standards
- (4-(Piperazine-1-carbonyl)phenyl)boronic acid (CAS 1003043-13-7)
- 4,4'-(Piperazine-1,4-diyl)dibenzaldehyde (CAS 10159-39-4)
- 3-(piperazine-1-carbonyl)-1,2-dihydropyridin-2-one (CAS 1016519-58-6)
- 3-(Piperazine-1-carbonyl)benzonitrile (CAS 1016684-78-8)
- Piperazine Impurity 7 (CAS 1025895-66-2)
- 2-(Piperazine-1-carbonyl)-1h-indole hydrochloride (CAS 1028800-67-0)
- Piperazine Impurity 15 (CAS 10430-90-7)
- 4-(Piperazine-1-sulfonyl)benzonitrile hydrochloride (CAS 1044761-22-9)
Recommended Standards
- 2-(Azepan-1-ylmethyl)benzonitrile (CAS 135277-09-7)
- 1-isocyanato-2,3-dimethylbenzene 1591-99-7 2,3-Dimethylphenylisocyanate 2,3-dimethylphenyl isocyanate CHEBI:63899 (CAS 1591-99-7)
- 2-ethyl-5H,6H,7H,8H-[1,2,4]triazolo[1,5-a]pyridin-8-amine (CAS 1368380-60-2)
- Ethyl 4-(2,3-dibromo-3-phenylpropanamido)benzoate (CAS 449788-70-9)
- (S)-1-(4-bromophenyl)but-3-en-1-amine (CAS 910545-67-4)
- ethyl 3-ethyl-1H-pyrazole-4-carboxylate (CAS 73981-23-4)
- (2R,3R,4R,5R)-2,5,6-trihydroxy-4-(((2S,3R,4S,5S,6R)-5-hydroxy-6-(hydroxymethyl)-4-(((2R,3R,4S,5R,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)-3-(((2S,3S,4R,5S,6S)-3,4,5-trihydroxy-6-methyltetrahydro-2H-pyran-2-yl)oxy)tetrahydro-2H-pyran-2-yl)oxy)-3-(((2S,3S,4R,5S,6S)-3,4,5-trihydroxy-6-methyltetrahydro-2H-pyran-2-yl)oxy)hexanal (CAS 72468-43-0)
- (E)-Cinnamyl formate (CAS 23510-72-7)
- Semaglutide impurity 61 (CAS CATO-C4X-222661)
- Semaglutide impurity 214 (CAS CATO-C4X-2226214)
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