3-Amino-4-cyclopropylthiophene-2-carboxylic acid CAS 1822680-39-6

Description

Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 3-Amino-4-cyclopropylthiophene-2-carboxylic acid.

3-Amino-4-cyclopropylthiophene-2-carboxylic acid (CAS 1822680-39-6), molecular formula C8H9NO2S and molecular weight 183.23 g/mol, is a CATO reference standard with documented purity and traceability.

3-Amino-4-cyclopropylthiophene-2-carboxylic acid (C8H9NO2S) contains a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage. The carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

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