4-(Aminomethyl)-3-chlorobenzonitrile CAS 182292-05-3
| CAS No. | 182292-05-3 |
| Molecular Formula | C8H7ClN2 |
| Molecular Weight | 166.61 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
CATO manufactures 4-(Aminomethyl)-3-chlorobenzonitrile under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
4-(Aminomethyl)-3-chlorobenzonitrile (CAS 182292-05-3) is a high-purity analytical reference standard with the molecular formula C8H7ClN2 and a molecular weight of 166.61 g/mol.
The molecular framework of 4-(Aminomethyl)-3-chlorobenzonitrile (C8H7ClN2) is characterized by a nitrogen-containing heterocyclic scaffold, a nitrile group, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
Physical & Chemical Properties
| Molecular Formula | C8H7ClN2 |
| Molecular Weight | 166.61 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2009 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
Related Aminomethyl Standards
- 5-(Aminomethyl)-2-chlorobenzonitrile (CAS 1261499-40-4)
- 3-(Aminomethyl)-4-chlorobenzonitrile (CAS 1261583-43-0)
- 3-(Aminomethyl)-2-chlorobenzonitrile (CAS 1261618-30-7)
- 3-(Aminomethyl)-5-chlorobenzonitrile (CAS 1261820-96-5)
- 2-(Aminomethyl)-5-chlorobenzonitrile (CAS 940062-12-4)
- 4-(Aminomethyl)-3-chlorobenzonitrile (CAS 202521-97-9)
- 4-(Aminomethyl)benzothioamide (CAS 404897-88-7)
- 4-(Aminomethyl)-n,n,6-trimethylpyrimidin-2-amine (CAS 1177480-26-0)
Recommended Standards
- 2-Chloro-3-methylimidazo[1,2-a]pyridine (CAS 1802819-48-2)
- 6-(Chloromethyl)pyrrolo[1,2-b]pyridazine (CAS 1824129-01-2)
- 2-(4-Amino-2-chlorophenyl)acetonitrile (CAS 180150-18-9)
- 2-Chloro-1-methyl-1H-benzo[d]imidazole (CAS 1849-02-1)
- Ambroxol (CAS 18683-91-5)
- (3-(Difluoromethyl)azetidin-3-yl)methanamine (CAS 1779935-18-0)
- 4,6-Dimethyl-5-nitropyrimidin-2-ol (CAS 1080650-02-7)
- 5-bromo-2,3-dihydro-1-benzofuran-7-sulfonamide (CAS 89819-41-0)
- Methyl 2-[4-(chlorosulfonyl)phenoxy]acetate (CAS 56077-78-2)
- 4-(2,4-Dichlorobenzoyl)-N-[3-(dimethylamino)propyl]-1H-pyrrole-2-carboxamide (CAS 338977-07-4)
- (2E)-N-Butyl-3-phenyl-2-propen-1-amine hydrochloride (CAS 1159698-11-9)
- Chloro[(S)-(+)-2,2'-bis(diphenylphosphino)-5,5',6,6',7,7',8,8'-octahydro-1,1'-binaphthyl](p-cymene)ruthenium(II) chloride (CAS 944451-27-8)
- 7-Methyl-1-(2-(p-tolyloxy)ethyl)indoline-2,3-dione (CAS 620932-12-9)
- HA Peptide (CAS 92000-76-5)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com