2-(3-Chloro-5-(trifluoromethyl)pyridin-2-yl)-5-fluoro-4-(methylthio)pyrimidine CAS 1823182-63-3
| CAS No. | 1823182-63-3 |
| Molecular Formula | C11H6ClF4N3S |
| Molecular Weight | 323.70 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 2-(3-Chloro-5-(trifluoromethyl)pyridin-2-yl)-5-fluoro-4-(methylthio)pyrimidine.
2-(3-Chloro-5-(trifluoromethyl)pyridin-2-yl)-5-fluoro-4-(methylthio)pyrimidine (CAS 1823182-63-3) is a high-purity analytical reference standard with the molecular formula C11H6ClF4N3S and a molecular weight of 323.70 g/mol.
2-(3-Chloro-5-(trifluoromethyl)pyridin-2-yl)-5-fluoro-4-(methylthio)pyrimidine (C11H6ClF4N3S) contains a nitrogen-containing heterocyclic scaffold, a nitrile group, sulfur-containing functionality, fluorine/chlorine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C11H6ClF4N3S |
| Molecular Weight | 323.70 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1995 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 3 |
| Sulfur Atoms | 1 |
Related Chloro Standards
- Methyl 3-chloro-2-(piperazin-1-yl)-5-(trifluoromethyl)isonicotinate (CAS 1147979-45-0)
- 4-Chloro-2-phenyl-6-(trifluoromethoxy)quinoline (CAS 1189106-94-2)
- 4-Chloro-2-phenyl-8-(trifluoromethoxy)quinoline (CAS 1189106-99-7)
- 4-Chloro-2-phenyl-7-(trifluoromethoxy)quinoline (CAS 1189107-66-1)
- 2-Chloro-3-(3-(trifluoromethyl)phenyl)quinolin-5-ol (CAS 1263386-30-6)
- 2-[(6-Chloro-4-trifluoromethyl-pyridin-2-yl)-methyl-hydrazono]-propionic acid ethyl ester (CAS 1311283-76-7)
- (E)-2-(3-chloro-5-(trifluoromethyl)pyridin-2-yl)-N-((dimethylamino)methylene)-2-methylhydrazine-1-carboxamide (CAS 321433-38-9)
- (E)-8-chloro-3-styryl-6-(trifluoromethyl)-[1,2,4]triazolo[4,3-a]pyridine (CAS 338795-37-2)
Recommended Standards
- (E)-N'-((3-chloro-5-(trifluoromethyl)pyridin-2-yl)glycyl)-N,N-dimethylformohydrazonamide (CAS 303148-16-5)
- 1-(5-(((3-Chloro-5-(trifluoromethyl)pyridin-2-yl)amino)methyl)-4,5-dihydroisoxazol-3-yl)ethan-1-ol (CAS 339110-69-9)
- 2-(4-(3-Chloro-5-(trifluoromethyl)pyridin-2-yl)piperazin-1-yl)acetic acid (CAS 400088-70-2)
- 2-[3-Chloro-5-(trifluoromethyl)pyridin-2-yl]-N-(morpholin-4-yl)acetamide (CAS 383147-70-4)
- 2-Amino-N-(((S)-2,3-dihydrobenzo[b][1,4]dioxin-2-yl)methyl)-N,3-dimethylbutanamide (CAS 1290198-35-4)
- 2-(4-(1,4-Dihydroxybutyl)phenyl)-2-methylpropanoic Acid (CAS 695165-49-2)
- 3-Bromo-4-iodo-1-methyl-1H-pyrazole-5-carbaldehyde (CAS 1807546-65-1)
- [2-(4-chlorophenoxy)ethyl]ethylamine hydrochloride (CAS 58506-57-3)
- Epigenetic Multiple Ligand (CAS 1020399-52-3)
- Bis[2-(benz[f]isoquinolin-4-yl-κN)-4-methylphenyl-κC](2,2,6,6-tetramethyl-3,5-heptanedionato-κO3,κO5)iridium (CAS 1616506-23-0)
- 4′-(Phenylmethoxy)[1,1′-biphenyl]-4-carbonitrile (CAS 117571-49-0)
- Tripelennamine N-Oxide (CAS 60317-19-3)
- 2,6-Dihydropyrrolo[2,3-g]indazole-7,8-dione (CAS 73907-94-5)
- Semaglutide impurity 65 (CAS CATO-C4X-222665)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com