4-Chloro-2-(3-chloro-5-(trifluoromethyl)pyridin-2-yl)-6,7-dihydro-5H-cyclopenta[d]pyrimidine CAS 1823183-94-3
| CAS No. | 1823183-94-3 |
| Molecular Formula | C13H8Cl2F3N3 |
| Molecular Weight | 334.12 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 4-Chloro-2-(3-chloro-5-(trifluoromethyl)pyridin-2-yl)-6,7-dihydro-5H-cyclopenta[d]pyrimidine is closely related to a nitrogen-containing heterocyclic scaffold, a nitrile group, fluorine/chlorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
4-Chloro-2-(3-chloro-5-(trifluoromethyl)pyridin-2-yl)-6,7-dihydro-5H-cyclopenta[d]pyrimidine (CAS 1823183-94-3) is a high-purity analytical reference standard with the molecular formula C13H8Cl2F3N3 and a molecular weight of 334.12 g/mol.
The molecular framework of 4-Chloro-2-(3-chloro-5-(trifluoromethyl)pyridin-2-yl)-6,7-dihydro-5H-cyclopenta[d]pyrimidine (C13H8Cl2F3N3) is characterized by a nitrogen-containing heterocyclic scaffold, a nitrile group, fluorine/chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 4-Chloro-2-(3-chloro-5-(trifluoromethyl)pyridin-2-yl)-6,7-dihydro-5H-cyclopenta[d]pyrimidine meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C13H8Cl2F3N3 |
| Molecular Weight | 334.12 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1995 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 3 |
Related Chloro Standards
- 2-(3-Chloro-5-(trifluoromethyl)pyridin-2-yl)-1-(4-chlorophenyl)ethan-1-one (CAS 1823182-92-8)
- (E)-3-chloro-2-(2-(4-chlorobenzylidene)hydrazinyl)-5-(trifluoromethyl)pyridine (CAS 338795-09-8)
- 3-Chloro-2-[(1E)-[2-(4-chlorophenyl)hydrazin-1-ylidene]methyl]-5-(trifluoromethyl)pyridine (CAS 338420-02-3)
- 4-Chloro-N-(2-chloro-5-(trifluoromethyl)phenyl)benzamide (CAS 3847-67-4)
- 6-Chloro-2-(4-chlorophenyl)-3-hydroxyquinoline-4-carboxylic acid (CAS 122262-53-7)
- 2-Chloro-N-(3-chloro-9,10-dihydro-9,10-dioxo-2-anthracenyl)acetamide (CAS 318272-33-2)
- 2-Chloro-N-(4-(4-chlorophenyl)-1,2,5-oxadiazol-3-yl)benzamide (CAS 866237-86-7)
- (4-(2-Chloro-6-fluorophenyl)-1H-pyrrol-3-yl)(4-chlorophenyl)methanone (CAS 477886-21-8)
Recommended Standards
- Decafluorobiphenyl (CAS 434-90-2)
- 2,6-dichloroisonicotinaldehyde 4-[3-(trifluoromethyl)phenyl]hydrazone (CAS 287917-72-0)
- Ethyl 2-acetoxy-5-iodobenzoate (CAS 857755-86-3)
- 3,5-Dichloro-N-(3-(trifluoromethyl)phenyl)benzamide (CAS 56661-34-8)
- 1-((6-Amino-5-nitropyrimidin-4-yl)amino)propan-2-ol (CAS 85446-52-2)
- 2-Isopropoxy-4-methyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine (CAS 1451391-04-0)
- 3-(4-Bromo-2-isopropylphenoxy)piperidinehydrochloride (CAS 1220032-71-2)
- (1-Phenyl-1h-pyrazol-5-yl)methanamine hydrochloride (CAS 2680614-87-1)
- 3-O-Methyl 4-Hydroxy Estradiol (CAS 5976-66-9)
- 4-(1-Ethylpyrrolidin-3-yl)oxyaniline (CAS 741716-20-1)
- 1-(1,3-dioxo-2,3-dihydro-1H-isoindol-2-yl)cyclopentane-1-carboxylic acid (CAS 51971-46-1)
- N-(2,3-dimethoxyphenyl)acetamide (CAS 121639-09-6)
- (3S,3aS,9bS)-9b-((4-Fluorophenyl)sulfonyl)-7-(perfluoropropan-2-yl)-2,3,3a,4,5,9b-hexahydro-1H-cyclopenta[a]naphthalene-3-carboxylic acid (CAS 2226317-41-3)
- Tirzepatide Impurity 10 (CAS CATO-C4X-324010)
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