3-(3-Amino-1H-pyrazol-4-yl)-6-(trifluoromethyl)pyrimidin-4(3H)-one CAS 1823184-32-2
| CAS No. | 1823184-32-2 |
| Molecular Formula | C8H6F3N5O |
| Molecular Weight | 245.16 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
3-(3-Amino-1H-pyrazol-4-yl)-6-(trifluoromethyl)pyrimidin-4(3H)-one (CAS 1823184-32-2) is a high-purity analytical reference standard with the molecular formula C8H6F3N5O and a molecular weight of 245.16 g/mol.
3-(3-Amino-1H-pyrazol-4-yl)-6-(trifluoromethyl)pyrimidin-4(3H)-one (C8H6F3N5O) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. Halogen substitution raises its density and boiling point; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 3-(3-Amino-1H-pyrazol-4-yl)-6-(trifluoromethyl)pyrimidin-4(3H)-one meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C8H6F3N5O |
| Molecular Weight | 245.16 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1995 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 5 |
Related Amino Standards
- 3-Amino-6-(trifluoromethyl)imidazo[1,2-a]pyridine-2-carboxylic acid (CAS 1368200-78-5)
- 2-Amino-3-(4-phosphonophenyl)propanoic acid (CAS 120667-22-3)
- (R)-2-Amino-3-(4-phosphonophenyl)propanoic acid (CAS 1241680-48-7)
- 3-Amino-5-(trifluoromethyl)benzofuran-2-carboxylic acid (CAS 1609354-00-8)
- 2-Amino-2-(4-phosphonophenyl)propanoic acid (CAS 169209-65-8)
- 3-Amino-6-(trifluoromethyl)benzofuran-2-carboxylic acid (CAS 1956332-30-1)
- (S)-2-Amino-3-(4-phosphonophenyl)propanoic acid (CAS 267236-68-0)
- 3-Amino-5-[4-fluoro-3-(trifluoromethyl)phenyl]pyrazole (CAS 1040724-42-2)
Recommended Standards
- 6-Methyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-2-carboxylic acid (CAS 1790365-86-4)
- 3-Bromo-2,2'-bithiophene (CAS 19690-69-8)
- 7-Methyl-2-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-5-carboxylic acid (CAS 1782824-90-1)
- (1-bromocyclobutyl)-phenyl-methanone (CAS 51175-78-1)
- 1-acetyl-4-fluoroazetidin-2-one (CAS 246181-66-8)
- 1-Hexadecylindoline-2,3-dione (CAS 28035-35-0)
- 4-(4-Hydroxypiperidin-1-yl)benzaldehyde (CAS 79421-44-6)
- 5-Hexyl-2,3-dimethylfuran (CAS 89932-16-1)
- 3-(Pyridin-2-yl)piperazin-2-one (CAS 1246548-67-3)
- 3-Chloro-N-(3-fluorobenzyl)-4-methoxyaniline (CAS 1019595-79-9)
- 5-Methyl-[2,3'-bipyridine]-5'-carbonitrile (CAS 1346686-75-6)
- 3-[(2-cyanoacetyl)amino]benzoic acid (CAS 178168-23-5)
- NIAD-4 (CAS 868592-56-7)
- Liraglutide Impurity 14 TFA Salt (CAS CATO-C4X-199214)
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