Benzyl 3,3-difluoro-4-(iodomethyl)-2-oxopyrrolidine-1-carboxylate CAS 1823264-85-2
| CAS No. | 1823264-85-2 |
| Molecular Formula | C13H12F2INO3 |
| Molecular Weight | 395.14 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
CATO manufactures Benzyl 3,3-difluoro-4-(iodomethyl)-2-oxopyrrolidine-1-carboxylate under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Benzyl 3,3-difluoro-4-(iodomethyl)-2-oxopyrrolidine-1-carboxylate (CAS 1823264-85-2), molecular formula C13H12F2INO3 and molecular weight 395.14 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of Benzyl 3,3-difluoro-4-(iodomethyl)-2-oxopyrrolidine-1-carboxylate (C13H12F2INO3) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine/iodine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
Physical & Chemical Properties
| Molecular Formula | C13H12F2INO3 |
| Molecular Weight | 395.14 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1995 |
| Halogen Content | F/I-containing |
| Nitrogen Atoms | 1 |
Related Benzyl Standards
- 3,4-difluoro-2-[(2-fluoro-4-iodophenyl)amino]-Benzoyl fluoride (CAS 934664-19-4)
- Methyl 1-(2,4-Difluoro-phenyl)-5-((4-tert-butyl-thiosemicarbazono)methyl)-1H-pyrazole-4-carboxylate (CAS 264233-05-8)
- 1,2-Difluoro-3,5-diiodo-4-methoxybenzene (CAS 1228093-55-7)
- 2,2'-(2,3-Difluoro-5-methoxy-1,4-phenylene)bis(4,4,5,5-tetramethyl-1,3,2-dioxaborolane) (CAS 2377608-79-0)
- 2,2'-(2,4-Difluoro-5-methoxy-1,3-phenylene)bis(4,4,5,5-tetramethyl-1,3,2-dioxaborolane) (CAS 2096332-73-7)
- 2,4-Difluoro-N-[5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-3-pyridinyl]benzenesulfonamide (CAS 1092565-35-9)
- Methyl 4-(2,7-difluoro-6-hydroxy-3-oxo-3H-xanthen-9-yl)-3-methylbenzoate (CAS 879288-18-3)
- 4-[Difluoro({[3-(trifluoromethyl)phenyl]sulfanyl})methyl]-6-methyl-2-phenylpyrimidine (CAS 306979-34-0)
Recommended Standards
- Ambroxol Cyclic Impurity-d5 Dihydrochloride (CAS 1794752-24-1)
- 3-((4-Bromo-3,5-bis(difluoromethyl)-1h-pyrazol-1-yl)methyl)-4-methoxybenzaldehyde (CAS 1005632-19-8)
- Diethyl 4-(bis(2-hydroxyethyl)amino)benzylphosphonate (CAS 16834-57-4)
- 3-(4-Bromophenyl)-5-((phenylselanyl)methyl)-4,5-dihydroisoxazole (CAS 828939-58-8)
- Ethyl 2-(3-chloro-5-(trifluoromethyl)pyridin-2-yl)-3-(dimethylamino)-3-oxopropanoate (CAS 338406-77-2)
- 4-[(Dimethylamino)methyl]quinolin-3-ol (CAS 37487-45-9)
- N-(3-chlorobenzyl)-2-(3-oxo-3,4-dihydro-2H-benzo[b][1,4]oxazine-6-carbonyl)benzamide (CAS 861212-84-2)
- 3-((4-Methoxyphenoxy)methyl)benzohydrazide (CAS 438221-87-5)
- 5-Aminopyridine-2(1H)-thione (CAS 27885-56-9)
- [2-(dimethylamino)ethyl](methyl)[3-(methylamino)propyl]amine (CAS 1342437-21-1)
- tert-Butyl (2-isopropylpiperidin-4-yl)carbamate (CAS 1780677-82-8)
- (R)-2-Amino-3-(3-fluoro-4-hydroxyphenyl)propanoicacid (CAS 64024-06-2)
- N-((1-Benzylpiperidin-4-yl)methyl)cyclopropanamine (CAS 920462-48-2)
- Liraglutide (13-21) TFA Salt (CAS CATO-C4X-19928)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com