4-Chloro-2-fluoro-6-methoxybenzonitrile CAS 1823366-82-0
| CAS No. | 1823366-82-0 |
| Molecular Formula | C8H5ClFNO |
| Molecular Weight | 185.58 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 185.58 g/mol gives 4-Chloro-2-fluoro-6-methoxybenzonitrile distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
4-Chloro-2-fluoro-6-methoxybenzonitrile (CAS 1823366-82-0) is a high-purity analytical reference standard with the molecular formula C8H5ClFNO and a molecular weight of 185.58 g/mol.
The molecular framework of 4-Chloro-2-fluoro-6-methoxybenzonitrile (C8H5ClFNO) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO manufactures 4-Chloro-2-fluoro-6-methoxybenzonitrile under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C8H5ClFNO |
| Molecular Weight | 185.58 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1995 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 1 |
Related Chloro Standards
- 6-Chloro-5-fluoroindolin-2-one (CAS 100487-74-9)
- 6-Chloro-2-fluoro-3-methoxybenzonitrile (CAS 1017777-72-8)
- 4-Chloro-5-fluoroindolin-2-one (CAS 103585-71-3)
- 4-Chloro-2-fluoro-3-methoxybenzonitrile (CAS 1126320-68-0)
- 5-Chloro-4-fluoroindolin-2-one (CAS 1222844-18-9)
- 5-Chloro-6-fluoroindolin-2-one (CAS 1222884-81-2)
- 7-Chloro-5-fluoroindolin-2-one (CAS 1260892-91-8)
- 6-Chloro-4-fluoroindolin-2-one (CAS 1309685-08-2)
Recommended Standards
- 4-Chloro-6-fluoroindolin-2-one (CAS 1690939-73-1)
- 1-(Chloromethyl)-4-Fluoro-2-Isocyanato-Benzene (CAS 67098-97-9)
- 2-(4-chloro-3-fluorophenoxy)acetonitrile (CAS 1553956-45-8)
- 2-(2-Chloro-4-fluorophenoxy)acetonitrile (CAS 24115-19-3)
- 4-Nitro-2-fluorophenyl triflate (CAS 1126423-47-9)
- 1-(1-(Fluoromethyl)-2-oxabicyclo[2.2.1]heptan-4-yl)ethan-1-one (CAS 2792155-89-4)
- [1-(Difluoromethyl)cyclobutyl]methanesulfonyl chloride (CAS 1784574-90-8)
- Fmoc-(R)-4-amino-5-phenylpentanoic acid (CAS 269078-74-2)
- N'-(4-Chloro-3-nitrobenzylidene)-4-((4-methylbenzyl)oxy)benzohydrazide (CAS 320423-64-1)
- (1R,3S)-3-methoxy-N-methylcyclopentan-1-amine (CAS 1268521-86-3)
- 4-(1H-1,2,3,4-tetrazol-1-yl)oxane-4-carboxylic acid (CAS 1909320-21-3)
- Methyl 5-((2-ethoxyphenyl)carbamoyl)-2-(furan-2-carboxamido)-4-methylthiophene-3-carboxylate (CAS 506416-41-7)
- 4-Cyclopropoxy-3-methoxy-5-(trifluoromethyl)pyridine (CAS 1243349-00-9)
- Tirzepatide Impurity 44 (CAS CATO-C4X-324044)
Why CATO?
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