4'-(Trifluoromethyl)spiro[cyclopropane-1,3'-indoline] CAS 1823881-89-5
| CAS No. | 1823881-89-5 |
| Molecular Formula | C11H10F3N |
| Molecular Weight | 213.20 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 4'-(Trifluoromethyl)spiro[cyclopropane-1,3'-indoline].
CATO supplies 4'-(Trifluoromethyl)spiro[cyclopropane-1,3'-indoline] (CAS 1823881-89-5), a certified reference material (molecular formula C11H10F3N, MW 213.20 g/mol) for analytical method development and quality control.
Structurally, 4'-(Trifluoromethyl)spiro[cyclopropane-1,3'-indoline] (C11H10F3N) contains a nitrogen-containing heterocyclic scaffold, a nitrile group, fluorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 6.0, corresponding to approximately 6 ring(s) or double-bond equivalent(s). With a molecular weight of 213.20 g/mol, it falls into the medium-molecular-weight range. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C11H10F3N |
| Molecular Weight | 213.20 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1995 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Related Trifluoromethyl Standards
- 4-[3-(trifluoromethyl)phenyl]butanenitrile (CAS 1057676-06-8)
- 5'-(Trifluoromethyl)spiro[cyclopropane-1,3'-indoline] (CAS 1211585-30-6)
- 7'-(Trifluoromethyl)spiro[cyclopropane-1,3'-indoline] (CAS 1516693-07-4)
- 6'-(Trifluoromethyl)spiro[cyclopropane-1,3'-indoline] (CAS 1823903-80-5)
- 2-METHYL-2-(4-(TRIFLUOROMETHYL)PHENYL)PROPANENITRILE (CAS 32445-87-7)
- 2-methyl-2-[3-(trifluoromethyl)phenyl]propanenitrile (CAS 89765-40-2)
- 5-(4-(Trifluoromethyl)phenyl)-3,4-dihydro-2H-pyrrole (CAS 72216-08-1)
- 2-Ethyl-6-(trifluoromethyl)morpholine-3-thione (CAS 1375473-03-2)
Recommended Standards
- (1H-Imidazol-1-yl)(pyrazolo[1,5-a]pyrimidin-3-yl)methanone (CAS 1710661-71-4)
- 3-(7H-Pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidin-7-yl)propanenitrile (CAS 1707563-49-2)
- (R)-1-(2-Methyl-3-(trifluoromethyl)phenyl)prop-2-yn-1-amine (CAS 2775437-19-7)
- 2,6-Di(2H-1,2,3-triazol-4-yl)pyridine (CAS 1542234-40-1)
- 3-(tert-Butyl)benzoyl Chloride (CAS 21900-36-7)
- (2R,5S)-2,5-Diphenylpiperazine (CAS 1259685-27-2)
- (R)-2-(5-chloro-2,3,4-trifluorophenyl)pyrrolidine (CAS 1241680-92-1)
- 4',4'''-(Thiophene-2,5-diyl)bis(([1,1'-biphenyl]-4-carbonitrile)) (CAS 868403-91-2)
- Benzyl-(3-trifluoromethoxy-propyl)-amine (CAS 1208079-19-9)
- Cocoyl Caprylocaprate (CAS 95912-86-0)
- Crizotinib Impurity 49 (CAS CATO-C4X-102549)
- 8-(4-Methoxyphenyl)-8-oxooctanenitrile (CAS 898786-68-0)
- 4,4-Difluoropentanoic acid (CAS 125110-82-9)
- Tirzepatide Impurity 34 (CAS CATO-C4X-324034)
Why CATO?
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