1-(3,5-Difluoropyridin-4-yl)piperazine CAS 1823903-88-3
| CAS No. | 1823903-88-3 |
| Molecular Formula | C9H11F2N3 |
| Molecular Weight | 199.20 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
1-(3,5-Difluoropyridin-4-yl)piperazine (CAS 1823903-88-3), molecular formula C9H11F2N3 and molecular weight 199.20 g/mol, is a CATO reference standard with documented purity and traceability.
1-(3,5-Difluoropyridin-4-yl)piperazine (C9H11F2N3) contains a nitrogen-containing heterocyclic scaffold, a nitrile group, fluorine substitution. Halogen substitution raises its density and boiling point; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 1-(3,5-Difluoropyridin-4-yl)piperazine meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C9H11F2N3 |
| Molecular Weight | 199.20 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1995 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 3 |
Related Difluoropyridin Standards
- Ethyl 2-(3,5-difluoropyridin-2-yl)acetate (CAS 940933-44-8)
- (E)-1-(3,5-Difluoropyridin-2-yl)-2-methoxyethanone oxime (CAS 1075757-31-1)
- 1-(3,5-Difluoropyridin-2-yl)-1H-pyrazol-3-amine (CAS 1566930-25-3)
- 2-(3,5-Difluoropyridin-2-yl)-2,2-difluoroethan-1-ol (CAS 1838637-14-1)
- (R)-1-(3,5-difluoropyridin-2-yl)-2-methoxyethan-1-amine (CAS 1075757-20-8)
- 1-(2,6-Difluoropyridin-3-yl)-2,2,2-trifluoroethanone (CAS 1707361-89-4)
- (2,6-Difluoropyridin-3-yl)trimethylsilane (CAS 685517-68-4)
- 1-(3,5-Difluoropyridin-2-yl)-2-methoxyethan-1-one (CAS 1075756-93-2)
Recommended Standards
- 1-Boc-pyrrolidine-2,4-dione (CAS 182352-59-6)
- 3-Fluoro-4-(methylsulfonyl)benzonitrile (CAS 185946-05-8)
- tert-Butyl 4-hydroxy-2-oxo-2,5-dihydro-1H-pyrrole-1-carboxylate (CAS 182352-48-3)
- Dimethyl (R)-2-(1-cyanopropan-2-yl)malonate (CAS 1889238-19-0)
- (5,6-Dichloropyridin-2-yl)methanamine (CAS 1256825-30-5)
- RJR 2403 Oxalate (CAS 220662-95-3)
- 1-Isopropyl-4,4-dimethylimidazolidine-2-thione (CAS 31596-21-1)
- 2-Bromo-3-(difluoromethoxy)benzotrifluoride (CAS 1807026-77-2)
- (S)-6-chloro-4-methyl-2,3-dihydro-1H-inden-1-amine (CAS 1213925-01-9)
- 2-(1h-1,2,4-Triazol-1-yl)pyridine-3-carboxylic acid (CAS 941400-53-9)
- 2-(2,4-Dimethoxyphenyl)-3-methylbutan-2-ol (CAS 6168-39-4)
- 3-Bromo-1-(propan-2-yl)-1H-pyrazole-4-carbaldehyde (CAS 1946813-61-1)
- Boc-p-Me-D-Phe-OH (CAS 80102-27-8)
- Insulin Lispro (CAS 133107-64-9)
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