6-Chlorofuro[3,4-c]pyridine-1,3-dione CAS 1823916-69-3
| CAS No. | 1823916-69-3 |
| Molecular Formula | C7H2ClNO3 |
| Molecular Weight | 183.55 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
6-Chlorofuro[3,4-c]pyridine-1,3-dione (CAS 1823916-69-3) is a high-purity analytical reference standard with the molecular formula C7H2ClNO3 and a molecular weight of 183.55 g/mol.
The molecular framework of 6-Chlorofuro[3,4-c]pyridine-1,3-dione (C7H2ClNO3) is characterized by an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
As a certified reference material (CRM), 6-Chlorofuro[3,4-c]pyridine-1,3-dione meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C7H2ClNO3 |
| Molecular Weight | 183.55 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO, water |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1995 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
Related Chlorofuro Standards
- 3-Chlorofuro[3,4-b]pyridine-5,7-dione (CAS 98278-86-5)
- 4-Chlorofuro[3,4-c]pyridine-1,3-dione (CAS 2306500-35-4)
- (5-Chlorofuro[2,3-b]pyridin-2-yl)methanol (CAS 1261365-42-7)
- (4-Chlorofuro[3,2-c]pyridin-2-yl)methanol (CAS 1315360-27-0)
- (5-Chlorofuro[3,2-b]pyridin-2-yl)methanol (CAS 1347814-95-2)
- (7-Chlorofuro[3,2-b]pyridin-5-yl)methanol (CAS 2769929-82-8)
- 4-Chlorofuro[3,2-c]pyridine-2-carbaldehyde (CAS 86518-07-2)
- 7-Chlorofuro[3,2-b]pyridine-5-carbaldehyde (CAS 2769929-83-9)
Recommended Standards
- 5-Chloro-2-cyano-3-nitropyridine (CAS 181123-11-5)
- 2-Chloro-5-nitropyridine-3-carbonitrile (CAS 31309-08-7)
- 4-Chloro-5-nitropicolinonitrile (CAS 1807254-01-8)
- 3-Chloro-5-nitropyridine-2-carbonitrile (CAS 488713-30-0)
- ethyl 2-bromo-1-(propan-2-yl)-1H-imidazole-4-carboxylate (CAS 1448869-67-7)
- 2-Amino-5-chloro-4-(difluoromethyl)pyridine-3-sulfonamide (CAS 1805101-96-5)
- 4,4'''-Bis((2-butyloctyl)oxy)-1,1':4',1'':4'',1'''-quaterphenyl (CAS 18434-08-7)
- 2-(2-phenylethyl)-3,4-dihydropyrimidin-4-one (CAS 1251377-90-8)
- Acibenzolar Acid Impurity 23 (CAS 135158-53-1)
- (6-Methoxy-2-(trifluoromethyl)pyridin-3-yl)boronic acid (CAS 2096338-27-9)
- 5-(4-Chloro-phenyl)-1H-pyrazole-3-carboxylic acid methyl ester (CAS 79508-09-1)
- 4-Chloro-5-fluoro-6-methoxypyrimidine (CAS 2012583-91-2)
- 2,2,6,6-Tetramethyl-2H-pyran-3,5(4H,6H)-dione (CAS 14744-26-4)
- (Leu31,Pro3?)-Neuropeptide Y (human, rat) trifluoroacetate salt (CAS 132699-73-1)
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