2,5-Dibromobenzofuran-3(2H)-one CAS 1823918-46-2
| CAS No. | 1823918-46-2 |
| Molecular Formula | C8H4Br2O2 |
| Molecular Weight | 291.92 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of 2,5-Dibromobenzofuran-3(2H)-one (C8H4Br2O2) is characterized by a carboxylic acid group, a hydroxyl group, an ether linkage, bromine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by the polarity and ionization state of its functional groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
2,5-Dibromobenzofuran-3(2H)-one (CAS 1823918-46-2) is a high-purity analytical reference standard with the molecular formula C8H4Br2O2 and a molecular weight of 291.92 g/mol.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C8H4Br2O2 |
| Molecular Weight | 291.92 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1995 |
| Halogen Content | Br-containing |
Related Dibromobenzofuran Standards
- 2,6-Dibromobenzofuran-3(2H)-one (CAS 1823370-21-3)
- 2,3-Dibromobenzofuran (CAS 64150-61-4)
- 3,5-Dibromobenzofuran (CAS 99660-97-6)
- 5,7-Dibromobenzofuran (CAS 23145-08-6)
- 1-(5,7-Dibromobenzofuran-2-yl)ethan-1-one (CAS 7203-79-4)
- Methyl 3,5-dibromobenzofuran-2-carboxylate (CAS 1355190-08-7)
- Ethyl 5,7-dibromobenzofuran-2-carboxylate (CAS 91182-70-6)
- (5,7-Dibromobenzofuran-2-yl)(phenyl)methanone (CAS 75630-71-6)
Recommended Standards
- 2,5-Dibromoterephthalaldehyde (CAS 63525-48-4)
- 5-Bromo-1,3-dichloro-2-(difluoromethoxy)benzene (CAS 929621-36-3)
- 4,6-Dibromoisophthalaldehyde (CAS 97094-37-6)
- 1-Bromo-2-chloro-3-[chloro-(difluoro)methoxy]benzene (CAS 1417568-86-5)
- Octahydro-1H-cyclopenta[b]pyridin-5-ol (CAS 1784613-47-3)
- Chroman-4-ylhydrazine (CAS 1016730-81-6)
- 2-(Acetyloxy)benzoic Acid 4-Methylphenyl Ester (CAS 52602-10-5)
- 1-((1-(2-Chloro-4-fluorophenyl)ethyl)amino)propan-2-ol (CAS 1158053-78-1)
- Methyl propylglycinate (CAS 209907-26-6)
- Ethyl N-[(2E)-2-{[(2-{4-[3-chloro-5-(trifluoromethyl)pyridin-2-yl]piperazin-1-yl}-5-(trifluoromethyl)phenyl)amino]methylidene}-2-cyanoacetyl]carbamate (CAS 338415-42-2)
- 1-(3-Ethynylphenyl)cyclopropane-1-carbonitrile (CAS 1314786-11-2)
- 2,3-Bis(methylamino)phenol (CAS 1243442-24-1)
- 4-Chloro-3-cyano-2-methylbenzene-1-sulfonyl chloride (CAS 1807190-06-2)
- Semaglutide impurity 244(Fmoc-His(Fmoc)-Aib-OH) (CAS CATO-C4X-2226244)
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