3-Chloro-7-fluoro-6-methoxyquinoline CAS 1823924-52-2
| CAS No. | 1823924-52-2 |
| Molecular Formula | C10H7ClFNO |
| Molecular Weight | 211.62 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 3-Chloro-7-fluoro-6-methoxyquinoline is closely related to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
3-Chloro-7-fluoro-6-methoxyquinoline (CAS 1823924-52-2), molecular formula C10H7ClFNO and molecular weight 211.62 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 3-Chloro-7-fluoro-6-methoxyquinoline (C10H7ClFNO) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 3-Chloro-7-fluoro-6-methoxyquinoline under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C10H7ClFNO |
| Molecular Weight | 211.62 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1995 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 1 |
Related Chloro Standards
- 2-(4-Chloro-1h-pyrazol-1-yl)-5-fluoroaniline (CAS 1006468-20-7)
- 4-(4-Chloro-1h-pyrazol-1-yl)-3-fluoroaniline (CAS 1006960-83-3)
- (2-Chloro-6-fluoroquinolin-3-yl)methanol (CAS 1017403-67-6)
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Recommended Standards
- 3-Chloro-6-fluoro-7-methoxyisoquinoline (CAS 1698813-47-6)
- 3-Chloro-8-fluoro-6-methoxyquinoline (CAS 1823940-04-0)
- 8-Chloro-6-fluoro-2-methylquinazolin-4-amine (CAS 1691898-85-7)
- 3-Chloro-6-fluoro-8-methoxyquinoline (CAS 1823963-58-1)
- Z-Lys-OH (CAS 2212-75-1)
- 2-Chloro-4-chloromethyl-3-(trifluoromethyl)pyridine (CAS 1227596-03-3)
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