1-Chloro-4-(trimethylsilyl)-3-butyn-2-one CAS 18245-82-4
| CAS No. | 18245-82-4 |
| Molecular Formula | C7H11ClOSi |
| Molecular Weight | 174.70 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO supplies 1-Chloro-4-(trimethylsilyl)-3-butyn-2-one (CAS 18245-82-4), a certified reference material (molecular formula C7H11ClOSi, MW 174.70 g/mol) for analytical method development and quality control.
The molecular framework of 1-Chloro-4-(trimethylsilyl)-3-butyn-2-one (C7H11ClOSi) is characterized by a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the polarity and ionization state of its functional groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
As a certified reference material (CRM), 1-Chloro-4-(trimethylsilyl)-3-butyn-2-one meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C7H11ClOSi |
| Molecular Weight | 174.70 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | Stable under recommended storage conditions |
| Degree of Unsaturation (DBE) | 2.0 |
| CAS Registry Year (est.) | 1962 |
| Halogen Content | Cl-containing |
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Recommended Standards
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- Methyl 4-((5,8-difluoroquinolin-4-yl)amino)benzoate (CAS 1315353-25-3)
- tert-butyl N-(1H-imidazol-2-yl)-N-methylcarbamate (CAS 1936593-51-9)
- BAM-12P (CAS 75513-71-2)
- Ethyl 4-(allylamino)-2-phenylpyrimidine-5-carboxylate (CAS 76360-64-0)
- N-((1-(4-Fluorophenyl)-1H-tetrazol-5-yl)methyl)-2-phenoxyacetamide (CAS 946360-83-4)
- Semaglutide impurity 91 (CAS CATO-C4X-222691)
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