6-Fluoro-2,5-dimethylpyrimidin-4-amine CAS 18260-68-9

Purity 97%+In StockPharmaceutical Standards
CAS No.18260-68-9
Molecular FormulaC6H8FN3
Molecular Weight141.15 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

6-Fluoro-2,5-dimethylpyrimidin-4-amine CAS 18260-68-9 chemical structure

Description

The occurrence of 6-Fluoro-2,5-dimethylpyrimidin-4-amine is closely related to a nitrile group, fluorine substitution, an aromatic ring system in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.

6-Fluoro-2,5-dimethylpyrimidin-4-amine (CAS 18260-68-9), molecular formula C6H8FN3 and molecular weight 141.15 g/mol, is a CATO reference standard with documented purity and traceability.

6-Fluoro-2,5-dimethylpyrimidin-4-amine (C6H8FN3) contains a nitrile group, fluorine substitution, an aromatic ring system. Halogen substitution raises its density and boiling point; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

Molecular FormulaC6H8FN3
Molecular Weight141.15 g/mol
Purity97%+
StorageStore at 2-8°C, protect from light, keep tightly closed to prevent evaporation
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light
Degree of Unsaturation (DBE)4.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1962
Halogen ContentF-containing
Nitrogen Atoms3

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