Tenofovir Impurity 67 CAS 182626-47-7
| CAS No. | 182626-47-7 |
| Molecular Formula | C8H11N5O |
| Molecular Weight | 193.21 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
As a process- or degradation-related impurity, Tenofovir Impurity 67 (CAS 182626-47-7, C8H11N5O) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
The molecular framework of Tenofovir Impurity 67 (C8H11N5O) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C8H11N5O |
| Molecular Weight | 193.21 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (faint amine-like odor) |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2009 |
| Nitrogen Atoms | 5 |
Related Tenofovir Standards
- Tenofovir alafenamide impurity N1 (CAS 16958-60-4)
- Tenofovir Impurity 110 (CAS 20776-34-5)
- Tenofovir Impurity 24 (CAS 14047-28-0)
- Tenofovir Disoproxil Impurity 35 (CAS 14047-27-9)
- Tenofovir disoproxil Impurity 41 (CAS 1244022-52-3)
- Tenofovir Impurity 66 (CAS 36817-69-3)
- Tenofovir Impurity 77 (CAS 1643116-22-6)
- Tenofovir disoproxil Impurity 99 (CAS CATO-C4X-107699)
Recommended Standards
- N-Nitroso Buspirone EP Impurity A (CAS 872826-80-7)
- S-(2-Carboxyethyl)-L-cysteine (CAS 100429-59-2)
- 3-phenylthiazolidine-2,4-dione (CAS 1010-53-3)
- 4158AF 6-Amino-5-propyl-[1,2,4]triazolo[1,5-a]-pyrimidin-7-ol 947010-62-0 C8H11N5O (CAS 947010-62-0)
- Sitafloxacin Impurity 31 (CAS CATO-C4X-115531)
- Ensifentrine impurity 23 (CAS 43113-25-3)
- Nintedanib Impurity 163 (CAS CATO-C4X-1814163)
- 1,2-Dibromo-3-methylbutane (CAS 10288-13-8)
- 4-Chloro-2-hydroxybenzamide (CAS 37893-37-1)
- 5-Propyl-3,5-dihydro-4H-pyridazino[4,5-b]indol-4-one (CAS 896629-75-7)
- 2-(Ethylsulfanyl)-5-[2-(methylsulfanyl)phenyl]-1,3,4-oxadiazole (CAS 339015-35-9)
- 2-Chloroinosine 3’,4’,6’-Triacetate (CAS 41623-86-3)
- 4-(((5-(2-ethoxycarbonyl-1H-indol-5-yl)-1-methylpyrazole-3-carbonyl)amino)methyl)benzoic acid (CAS 1222173-37-6)
- [Glu]17-Liraglutide (CAS CATO-C4X-199236)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com