1-(3-Chloropropyl)-1,1,3,3,3-pentamethyldisiloxane CAS 18291-27-5
| CAS No. | 18291-27-5 |
| Molecular Formula | C8H21ClOSi2 |
| Molecular Weight | 224.88 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Owing to a hydroxyl group, an ether linkage, chlorine substitution, 1-(3-Chloropropyl)-1,1,3,3,3-pentamethyldisiloxane is typically white to off-white crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 224.88 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
CATO supplies 1-(3-Chloropropyl)-1,1,3,3,3-pentamethyldisiloxane (CAS 18291-27-5), a certified reference material (molecular formula C8H21ClOSi2, MW 224.88 g/mol) for analytical method development and quality control.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C8H21ClOSi2 |
| Molecular Weight | 224.88 g/mol |
| Purity | 97%+ |
| Storage | Store at room temperature, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | Stable under recommended storage conditions |
| Degree of Unsaturation (DBE) | -2.0 |
| CAS Registry Year (est.) | 1962 |
| Halogen Content | Cl-containing |
Related Chloropropyl Standards
- 2-(3-Chloropropyl)-6-fluoroquinazoline (CAS 2006277-67-2)
- 1-(3-Chloropropyl)-3,4-dihydroquinolin-2(1H)-one (CAS 79145-37-2)
- 2-(3-Chloropropyl)isoindoline-1,3-dione (CAS 42251-84-3)
- 5-(3-Chloropropyl)-3-(pyridin-3-yl)-1,2,4-oxadiazole (CAS 923227-07-0)
- 5-(3-Chloropropyl)-3-(pyridin-4-yl)-1,2,4-oxadiazole (CAS 923108-22-9)
- Ethyl 4-(3-chloropropyl)benzoate (CAS 86911-10-6)
- 3-(2-Chloropropyl)quinazolin-4(3H)-one (CAS 5270-99-5)
- 5-(3-Chloropropyl)-1-Phenyl-1H-1,2,3,4-Tetrazole (CAS 73963-34-5)
Recommended Standards
- 3-Bromo-5-fluorobenzeneboronic acid 3-Bromo-5-fluorophenylboronic acid 3-bromo-5-fluorobenzeneboronic acid 95 3-bromo-5-fluorobenzeneboronic acid 95% 849062-37-9 (CAS 849062-37-9)
- 3,4-Dibromo-1H-pyrrole (CAS 95972-59-1)
- 216393-64-5 4 - Bromo - 2 - fluorophenylboronic acid 4-Bromo-2-fluorobenzeneboronic acid boronic acid, (4-bromo-2-fluorophenyl)- (CAS 216393-64-5)
- Butyl(mercapto)stannanone (CAS 26410-42-4)
- Benzo[d]thiazole-4-carbonitrile (CAS 1510701-21-9)
- 3,3'-Dimethyl-[4,5'-biisoxazol]-5(2H)-one (CAS 17281-33-3)
- 6-(1-Methyl-1H-pyrazol-5-yl)pyridazin-3-amine (CAS 1487971-57-2)
- 5-(1-Acetylpyrrolidin-2-yl)pyridin-2(1H)-one (CAS 1352514-92-1)
- 2-Amino-6-(bromomethyl)-3-(difluoromethyl)isonicotinaldehyde (CAS 1805345-72-5)
- 5-((6-Hydroxy-2,3-dihydrobenzofuran-5-yl)methyl)-6-methyl-2-phenylpyrimidin-4(1H)-one (CAS 18006-89-8)
- Roxadustat-d5 (CAS 2043026-13-5)
- Benzenamine, 2-nitro-4-(3-oxetanyloxy)- (CAS 1430938-04-7)
- H-Leu-Leu-NH? · HCl (CAS 73237-75-9)
- D-Pro36-Tirzepatide (CAS CATO-CPTD788903)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com