Trimethylsilyl 2-chloroacetate CAS 18293-71-5
| CAS No. | 18293-71-5 |
| Molecular Formula | C5H11ClO2Si |
| Molecular Weight | 166.68 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 166.68 g/mol gives Trimethylsilyl 2-chloroacetate distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
Trimethylsilyl 2-chloroacetate (CAS 18293-71-5) is a high-purity analytical reference standard with the molecular formula C5H11ClO2Si and a molecular weight of 166.68 g/mol.
Trimethylsilyl 2-chloroacetate (C5H11ClO2Si) contains a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution. Halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), Trimethylsilyl 2-chloroacetate meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C5H11ClO2Si |
| Molecular Weight | 166.68 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 0.0 |
| CAS Registry Year (est.) | 1962 |
| Halogen Content | Cl-containing |
Related Trimethylsilyl Standards
- N-(Trimethylsilyl)pyridin-3-amine (CAS 132735-42-3)
- 3-(Trimethylsilyl)pyridin-4-amine (CAS 17379-44-1)
- 4-(Trimethylsilyl)phenol (CAS 13132-25-7)
- 2-(Trimethylsilyl)phenol (CAS 15288-53-6)
- 3-(Trimethylsilyl)pyridin-2(1H)-one (CAS 17379-48-5)
- N-(Trimethylsilyl)methanesulfonamide (CAS 999-96-2)
- 3-Methyl-2-(trimethylsilyl)pyridine (CAS 13737-07-0)
- 5-Methyl-2-(trimethylsilyl)pyridine (CAS 13737-09-2)
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