4-(Trimethylsilyl)pyridine CAS 18301-46-7

Purity 97%+In StockPharmaceutical Standards
CAS No.18301-46-7
Molecular FormulaC8H13NSi
Molecular Weight151.28 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

4-(Trimethylsilyl)pyridine CAS 18301-46-7 chemical structure

Description

Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.

CATO supplies 4-(Trimethylsilyl)pyridine (CAS 18301-46-7), a certified reference material (molecular formula C8H13NSi, MW 151.28 g/mol) for analytical method development and quality control.

The molecular framework of 4-(Trimethylsilyl)pyridine (C8H13NSi) is characterized by a nitrile group. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

Molecular FormulaC8H13NSi
Molecular Weight151.28 g/mol
AppearanceWhite to pale yellow crystalline powder. (faint amine-like odor)
Purity97%+
StorageStore at 2-8°C, protect from light
Solubility (reference)Soluble in methanol, acetonitrile, DMSO
StabilityLight-sensitive; avoid direct strong light
Degree of Unsaturation (DBE)3.0
UV AbsorptionUV-absorbing
CAS Registry Year (est.)1962
Nitrogen Atoms1

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