(S)-Pyrrolidine-2-carboxylic acid (2-methoxy-phenyl)-amide CAS 183127-66-4
| CAS No. | 183127-66-4 |
| Molecular Formula | C12H16N2O2 |
| Molecular Weight | 220.27 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of (S)-Pyrrolidine-2-carboxylic acid (2-methoxy-phenyl)-amide (C12H16N2O2) is characterized by an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
CATO supplies (S)-Pyrrolidine-2-carboxylic acid (2-methoxy-phenyl)-amide (CAS 183127-66-4), a certified reference material (molecular formula C12H16N2O2, MW 220.27 g/mol) for analytical method development and quality control.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), (S)-Pyrrolidine-2-carboxylic acid (2-methoxy-phenyl)-amide meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C12H16N2O2 |
| Molecular Weight | 220.27 g/mol |
| Appearance | Off-white to pale yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2009 |
| Nitrogen Atoms | 2 |
Related S Standards
- 6-(Pyrrolidine-1-carbonyl)pyridine-2-carboxylic acid (CAS 1153759-48-8)
- 2-(Pyrrolidine-1-carbothioylsulfanyl)acetohydrazide (CAS 374637-35-1)
- 2-((Pyrrolidine-1-carbonothioyl)thio)propanoic acid (CAS 53278-49-2)
- 3-((Pyrrolidine-1-carbonothioyl)thio)propanoic acid (CAS 81994-77-6)
- Methyl 2-((pyrrolidine-1-carbonothioyl)thio)acetate (CAS 852399-75-8)
- 1-(Pyrrolidine-1-sulfonyl)piperazine (CAS 923681-40-7)
- 5-Phenyl-pyrrolidine-3-carboxylic acid ethyl ester (CAS 92041-21-9)
- 4-(Pyrrolidine-1-sulfonyl)butanoic acid (CAS 1018283-85-6)
Recommended Standards
- Chloro(methoxy)dimethylsilane (CAS 1825-68-9)
- (2E)-N-(4-butylphenyl)-2-(hydroxyimino)acetamide (CAS 18331-68-5)
- Methyl 1-(pyridin-3-yl)piperidine-3-carboxylate (CAS 1823509-89-2)
- Boc-Aminooxy-PEG1-C2-NH2 (CAS 1844894-82-1)
- 5-Chloro-2-pivalamidobenzoic acid (CAS 351896-22-5)
- 1,1-Dimethylethyl N-[(4-iodophenyl)methyl]carbamate (CAS 189132-01-2)
- Ethyl 4-amino-1-(fluoromethyl)cyclohexane-1-carboxylate (CAS 2387595-35-7)
- 3-Amino-6-iodopyrazine-2-carboxylic acid (CAS 875781-48-9)
- 2526AE 400073-81-6 C14H11F3N2O N-(2-Aminophenyl)-4-(trifluoromethyl)benzamide (CAS 400073-81-6)
- 1-(2-Methoxylphenyl)-3,3-dimethylbutan-2-one (CAS 75508-73-5)
- (1R,4R)-5-Boc-2-oxa-5-azabicyclo[2.2.1]heptan-3-one (CAS 848488-70-0)
- 4'-Methoxy-[1,1'-biphenyl]-2-carboxylicacid (CAS 18110-71-9)
- (R)-3-((tert-Butoxycarbonyl)amino)-4-(2,4-dichlorophenyl)butanoic acid (CAS 269396-53-4)
- Semaglutide impurity 63 (CAS CATO-C4X-222663)
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