2-(1,3-Dioxoisoindolin-2-yl)-N-(4-((3-ethynylphenyl)amino)quinazolin-6-yl)ethanesulfonamide CAS 183321-69-9

Description

Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 2-(1,3-Dioxoisoindolin-2-yl)-N-(4-((3-ethynylphenyl)amino)quinazolin-6-yl)ethanesulfonamide.

CATO supplies 2-(1,3-Dioxoisoindolin-2-yl)-N-(4-((3-ethynylphenyl)amino)quinazolin-6-yl)ethanesulfonamide (CAS 183321-69-9), a certified reference material (molecular formula C26H19N5O4S, MW 497.53 g/mol) for analytical method development and quality control.

Owing to a steroid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage, 2-(1,3-Dioxoisoindolin-2-yl)-N-(4-((3-ethynylphenyl)amino)quinazolin-6-yl)ethanesulfonamide is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 497.53 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

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