Methyl 4-chloroquinazoline-7-carboxylate CAS 183322-47-6
| CAS No. | 183322-47-6 |
| Molecular Formula | C10H7ClN2O2 |
| Molecular Weight | 222.63 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Based on its molecular formula C10H7ClN2O2, Methyl 4-chloroquinazoline-7-carboxylate contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 222.63 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
CATO supplies Methyl 4-chloroquinazoline-7-carboxylate (CAS 183322-47-6), a certified reference material (molecular formula C10H7ClN2O2, MW 222.63 g/mol) for analytical method development and quality control.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), Methyl 4-chloroquinazoline-7-carboxylate meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C10H7ClN2O2 |
| Molecular Weight | 222.63 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2009 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
Related Methyl Standards
- Methyl 2-chloroquinazoline-6-carboxylate (CAS 1036755-96-0)
- Methyl 2-chloroquinazoline-8-carboxylate (CAS 1217269-81-2)
- Methyl 2-Chloroquinazoline-5-carboxylate (CAS 1221288-22-7)
- Methyl 4-Chloroquinazoline-5-carboxylate (CAS 1260890-93-4)
- Methyl 4-chloroquinazoline-2-carboxylate (CAS 1284130-45-5)
- 7-Chloroquinazoline-4-acetic Acid (CAS 1783794-98-8)
- 2-Chloroquinazoline-4-acetic Acid (CAS 1783795-26-5)
- Methyl 2-chloroquinazoline-4-carboxylate (CAS 1797884-06-0)
Recommended Standards
- Methyl 6-chloroquinazoline-4-carboxylate (CAS 1823935-13-2)
- 5-(2-Chlorobenzoyl)-2-methyl-2H-1,2,3,4-tetrazole (CAS 1858599-02-6)
- methyl 6-chloro-5-nitro-pyridine-2-carboxylate (CAS 1803583-09-6)
- 4-Chloro-6-methyl-8-nitroquinoline (CAS 190140-02-4)
- 4-Bromo-1,1,1,4,4-pentafluoro-2-(trifluoromethyl)but-2-ene (CAS 885276-66-4)
- 1246815-66-6 Rhein Disulfate (CAS 1246815-66-6)
- 2-(4-(4-Fluorophenyl)piperazin-1-yl)-N-(4-phenoxyphenyl)acetamide (CAS 524063-21-6)
- tert-Butyl (E)-prop-1-en-1-ylcarbamate (CAS 119973-54-5)
- Methyl 3-((cyclohexylamino)methyl)-4-methoxybenzoate (CAS 886504-38-7)
- 3-{6-methylimidazo[2,1-b][1,3]thiazol-3-yl}propanoic acid hydrobromide (CAS 1394040-73-3)
- (S)-4-((9H-fluoren-9-yl)methoxy)-2-((((9H-fluoren-9-yl)methoxy)carbonyl)amino)-4-oxobutanoic acid (CAS 608512-85-2)
- 1-(3-Isopropoxyphenyl)-1-(1H-pyrrol-2-yl)ethan-1-ol (CAS 1443350-74-0)
- 2-Formyl-5-(3-oxomorpholino)benzonitrile (CAS 1260677-62-0)
- Pancreatic Polypeptide (rat) (CAS 90419-12-8)
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