5-Ethynyl-2-methylaniline CAS 183322-53-4

Description

Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 5-Ethynyl-2-methylaniline.

CATO supplies 5-Ethynyl-2-methylaniline (CAS 183322-53-4), a certified reference material (molecular formula C9H9N, MW 131.17 g/mol) for analytical method development and quality control.

The molecular framework of 5-Ethynyl-2-methylaniline (C9H9N) is characterized by a nitrogen-containing heterocyclic scaffold, a nitrile group. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

As a certified reference material (CRM), 5-Ethynyl-2-methylaniline meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

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