4-Hydroxy-5-phenyl-1H-pyrimidin-6-one CAS 18337-64-9

Purity 97%+In StockPharmaceutical Standards
CAS No.18337-64-9
Molecular FormulaC10H8N2O2
Molecular Weight188.18 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

4-Hydroxy-5-phenyl-1H-pyrimidin-6-one CAS 18337-64-9 chemical structure

Description

Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 4-Hydroxy-5-phenyl-1H-pyrimidin-6-one.

4-Hydroxy-5-phenyl-1H-pyrimidin-6-one (CAS 18337-64-9) is a high-purity analytical reference standard with the molecular formula C10H8N2O2 and a molecular weight of 188.18 g/mol.

The molecular framework of 4-Hydroxy-5-phenyl-1H-pyrimidin-6-one (C10H8N2O2) is characterized by an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).

Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.

CATO manufactures 4-Hydroxy-5-phenyl-1H-pyrimidin-6-one under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.

Physical & Chemical Properties

Molecular FormulaC10H8N2O2
Molecular Weight188.18 g/mol
AppearancePale yellow to yellow crystalline powder. (faint amine-like odor)
Purity97%+
StorageStore at 2-8°C, protect from light, keep sealed and dry
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening
Degree of Unsaturation (DBE)8.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1962
Nitrogen Atoms2

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