PF-06456384 trihydrochloride CAS 1834610-75-1
| CAS No. | 1834610-75-1 |
| Molecular Formula | C35H32F3N7O3S2 |
| Molecular Weight | 719.80 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
PF-06456384 trihydrochloride (CAS 1834610-75-1) is a high-purity analytical reference standard with the molecular formula C35H32F3N7O3S2 and a molecular weight of 719.80 g/mol.
Owing to a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage, fluorine substitution, PF-06456384 trihydrochloride is typically pale yellow to yellow amorphous powder. Its solid-state physicochemical attributes — including a molecular weight of 719.80 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), PF-06456384 trihydrochloride meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C35H32F3N7O3S2 |
| Molecular Weight | 719.80 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 22.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1995 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 7 |
| Sulfur Atoms | 2 |
Related PF Standards
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Recommended Standards
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- FV 100 N-Fmoc (CAS 1269409-87-1)
- 1,1'-((2E,2'E)-3,3'-(((((2-Hydroxyethyl)azanediyl)bis(ethane-2,1-diyl))bis(oxy))bis(3,5-dimethoxy-4, (CAS 2734138-17-9)
- cIAP1 Ligand-Linker Conjugates 14 (CAS 1351169-40-8)
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- ethyl 2-amino-3-(4-chlorophenyl)-3-hydroxypropanoate hydrochloride (CAS 2031259-14-8)
- 3-Methyl-5-(morpholin-4-yl)pyridin-2-amine (CAS 1554988-88-3)
- N-[4-(2-Methoxyethoxy)benzyl]-1-hexadecanamine (CAS 1040687-33-9)
- tert-Butyl 8-oxo-5-azaspiro[3.5]nonane-5-carboxylate (CAS 778646-92-7)
- 4-Bromo-5-chloro-2-methylbenzoic acid (CAS 1349716-38-6)
- 1-Aminocyclohexanecarbonitrile (CAS 5496-10-6)
- Methyl 2-(4-methylquinolin-8-yl)acetate (CAS 1383625-63-5)
- Semaglutide impurity 41 (CAS CATO-C4X-222641)
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