4-Nitro-7-(piperidin-1-yl)benzo[c][1,2,5]oxadiazole CAS 18378-22-8

Purity 97%+In StockPharmaceutical Standards
CAS No.18378-22-8
Molecular FormulaC11H12N4O3
Molecular Weight248.24 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

4-Nitro-7-(piperidin-1-yl)benzo[c][1,2,5]oxadiazole CAS 18378-22-8 chemical structure

Description

Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 4-Nitro-7-(piperidin-1-yl)benzo[c][1,2,5]oxadiazole.

4-Nitro-7-(piperidin-1-yl)benzo[c][1,2,5]oxadiazole (CAS 18378-22-8), molecular formula C11H12N4O3 and molecular weight 248.24 g/mol, is a CATO reference standard with documented purity and traceability.

The molecular framework of 4-Nitro-7-(piperidin-1-yl)benzo[c][1,2,5]oxadiazole (C11H12N4O3) is characterized by an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

CATO manufactures 4-Nitro-7-(piperidin-1-yl)benzo[c][1,2,5]oxadiazole under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.

Physical & Chemical Properties

Molecular FormulaC11H12N4O3
Molecular Weight248.24 g/mol
AppearancePale yellow to yellow crystalline powder
Purity97%+
StorageStore at 2-8°C, protect from light, keep sealed and dry
Solubility (reference)Soluble in methanol, ethanol, DMSO
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening
Degree of Unsaturation (DBE)8.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1962
Nitrogen Atoms4

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