1-methylindole-2-sulfonyl chloride CAS 184039-88-1
| CAS No. | 184039-88-1 |
| Molecular Formula | C9H16ClNO2S |
| Molecular Weight | 237.75 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
1-methylindole-2-sulfonyl chloride (CAS 184039-88-1), molecular formula C9H16ClNO2S and molecular weight 237.75 g/mol, is a CATO reference standard with documented purity and traceability.
Owing to an amide group, a sulfone group, a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution, 1-methylindole-2-sulfonyl chloride is typically white to off-white crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 237.75 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
As a certified reference material (CRM), 1-methylindole-2-sulfonyl chloride meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C9H16ClNO2S |
| Molecular Weight | 237.75 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 2.0 |
| CAS Registry Year (est.) | 2009 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
| Sulfur Atoms | 1 |
Related methylindole Standards
- 1-Boc-7-methylindole (CAS 442910-62-5)
- Ethyl 6-Methylindole-3-acetate (CAS 1783325-62-1)
- Ethyl 4-Methylindole-3-acetate (CAS 1859912-52-9)
- Ethyl 7-Methylindole-3-acetate (CAS 91957-22-1)
- 5-Methylindole-2-carboxylic acid ethyl ester (CAS 16382-15-3)
- 1 - Methylindole - 5 - boronic acid pinacol ester 1-Methyl-5-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-1H-indole 1-methyl-5-(4 1-methyl-5-(4,4,5,5-tetramethyl-1,2,3-dioxaborolan-2-yl)-1h-indole 1-methyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-indole 1-methyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1h-indazole 1-methylindole-5-boronic acid, pinacol ester 1H-indole, 1-methyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)- 2-dioxaborolan-2-yl)-1h-indole 837392-62-8 akos brn-1159 (CAS 837392-62-8)
- 1-methylindole-5-carbonyl isocyanate (CAS 2761279-32-5)
- Ethyl 6-Methylindole-3-carboxylate (CAS 100821-48-5)
Recommended Standards
- 2-methyl-1H-indole-5-sulfonyl chloride (CAS 1696428-12-2)
- Quinoline-8-sulfonyl chloride (CAS 18704-37-5)
- 4-(Chloromethyl)-2-(3-ethylphenyl)thiazole (CAS 1393576-93-6)
- 4-Chloro-6-(isopropylthio)quinoline (CAS 1912423-48-3)
- 2-(2-Benzoxazolylthio)-N-[2-(Cyclohexylamino)-2-Oxoethyl]-N-(2-Fluorophenyl)-Acetamide (CAS 606098-42-4)
- 3-(2-methylcyclopropyl)-1-phenyl-1H-pyrazol-5-amine (CAS 1152712-12-3)
- 1-[(3,5-Dimethyl-1H-pyrazol-1-yl)methyl]cyclobutan-1-ol (CAS 2126163-22-0)
- Tetrapyrido[3,2-a:2',3'-c:3'',2''-h:2''',3'''-j]phenazine (CAS 168646-52-4)
- N-(2-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-4-(trifluoromethyl)phenyl)acetamide (CAS 1374606-49-1)
- 1-(3,4-difluorophenyl)-2-methyl-2-(pyrrolidin-1-yl)propan-1-amine dihydrochloride (CAS 1461705-08-7)
- 2-Amino-1-(4-(tert-butyl)phenyl)ethanol (CAS 41870-80-8)
- 1,2-Dimethyl-1h-indole-3-sulfonamide (CAS 1368855-49-5)
- 3-(Methylamino)benzamide hydrochloride (CAS 2361676-45-9)
- Peptide Impurity 15 (CAS 1227750-69-7)
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