2-(Trimethylsilyl)-5-chlorothiophene CAS 18412-68-5

Description

The occurrence of 2-(Trimethylsilyl)-5-chlorothiophene is closely related to an organic framework in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.

2-(Trimethylsilyl)-5-chlorothiophene (CAS 18412-68-5) is a high-purity analytical reference standard with the molecular formula C13H22Si and a molecular weight of 206.40 g/mol.

The molecular framework of 2-(Trimethylsilyl)-5-chlorothiophene (C13H22Si) is characterized by an organic framework. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

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