5-(Chloromethyl)-1-methyl-3-(trifluoromethyl)-1H-pyrazole CAS 184358-63-2
| CAS No. | 184358-63-2 |
| Molecular Formula | C6H6ClF3N2 |
| Molecular Weight | 198.57 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 5-(Chloromethyl)-1-methyl-3-(trifluoromethyl)-1H-pyrazole.
5-(Chloromethyl)-1-methyl-3-(trifluoromethyl)-1H-pyrazole (CAS 184358-63-2) is a high-purity analytical reference standard with the molecular formula C6H6ClF3N2 and a molecular weight of 198.57 g/mol.
Structurally, 5-(Chloromethyl)-1-methyl-3-(trifluoromethyl)-1H-pyrazole (C6H6ClF3N2) contains a nitrile group, fluorine/chlorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 3.0, corresponding to approximately 3 ring(s) or double-bond equivalent(s). With a molecular weight of 198.57 g/mol, it falls into the medium-molecular-weight range. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 5-(Chloromethyl)-1-methyl-3-(trifluoromethyl)-1H-pyrazole under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C6H6ClF3N2 |
| Molecular Weight | 198.57 g/mol |
| Appearance | White to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 3.0 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 2009 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 2 |
Related Chloromethyl Standards
- 1-(Chloromethyl)-5-methyl-3-(trifluoromethyl)-1H-pyrazole (CAS 1006356-44-0)
- 4-(Chloromethyl)-1-methyl-3-(trifluoromethyl)-1H-pyrazole (CAS 1222556-79-7)
- 3-(chloromethyl)-1-methyl-5-(trifluoromethyl)-1H-pyrazole (CAS 1260658-92-1)
- 3-(Chloromethyl)-1-(2,2,2-trifluoroethyl)-1H-pyrazole (CAS 1260658-95-4)
- 5-(Chloromethyl)-1-(2,2,2-trifluoroethyl)-1H-pyrazole (CAS 1281984-44-8)
- 2-(Chloromethyl)-1-(2,2,2-trifluoroethyl)-1h-imidazole hydrochloride (CAS 135206-93-8)
- 4-(Chloromethyl)-1-(2,2,2-trifluoroethyl)-1h-pyrazole (CAS 405103-71-1)
- 1-(Chloromethyl)-2,3,4,5-tetrafluorobenzene (CAS 21622-18-4)
Recommended Standards
- 6-Chloro-3-nitro-imidazo[1,2-b]pyridazine (CAS 18087-76-8)
- 8-Chloro-[1,2,4]triazolo[4,3-a]pyrazine-3-carboxylic acid (CAS 1935512-03-0)
- 4-Chloro-5-nitro-1H-pyrazolo[3,4-b]pyridine (CAS 1638769-09-1)
- 1-azido-4-chloro-2-nitrobenzene (CAS 89284-67-3)
- (R)-1-(Pyrrolidin-2-yl)cyclopentanol (CAS 185246-69-9)
- 2-(2-Phenyl-1,3-thiazol-4-yl)-5-[3-(trifluoromethyl)phenyl]-1,3,4-oxadiazole (CAS 400083-60-5)
- 2-((5-Methylhexan-2-yl)amino)butan-1-ol (CAS 1042624-39-4)
- Isobebeerine (CAS 477-62-3)
- 3-Ethynyl-5-methoxypyridine (CAS 686768-50-3)
- 3-(Benzyloxy)pyrido[1,2-a]indole-10-carbonitrile (CAS 338981-94-5)
- (3-fluoro-4-methoxyphenyl)hydrazine (CAS 339264-51-6)
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- (E)-5-(4-(1H-1,2,4-triazol-1-yl)benzylidene)-2-morpholino-3,5-dihydro-4H-imidazol-4-one (CAS 939762-06-8)
- T-Peptide (CAS 2022956-62-1)
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