2-tert-Butyl-4-chloropyrimidine CAS 18436-67-4
| CAS No. | 18436-67-4 |
| Molecular Formula | C8H11ClN2 |
| Molecular Weight | 170.64 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), 2-tert-Butyl-4-chloropyrimidine meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
2-tert-Butyl-4-chloropyrimidine (CAS 18436-67-4), molecular formula C8H11ClN2 and molecular weight 170.64 g/mol, is a CATO reference standard with documented purity and traceability.
2-tert-Butyl-4-chloropyrimidine (C8H11ClN2) contains a nitrogen-containing heterocyclic scaffold, a nitrile group, chlorine substitution. Halogen substitution raises its density and boiling point; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
Physical & Chemical Properties
| Molecular Formula | C8H11ClN2 |
| Molecular Weight | 170.64 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1962 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
Recommended Standards
- 4-Chloro-N1,N1-dimethylbenzene-1,2-diamine (CAS 183251-88-9)
- 1-Chloro-3-ethoxy-5-methylbenzene (CAS 1881291-70-8)
- 4-Chloro-2,3-dimethylbenzyl alcohol (CAS 1826109-99-2)
- (4-Chloro-3,5-dimethylphenyl)methanol (CAS 18982-59-7)
- TERT-BUTYL 3-((1,3-DIOXOISOINDOLIN-2-YL)METHYL)BENZOATE (CAS 1312596-11-4)
- 3-(((5-Nitrofuran-2-yl)methylene)amino)thiazolidin-2-one (CAS 5407-75-0)
- 4-(Fluorosulfonyl)thiophene-2-carboxylic acid (CAS 1384428-37-8)
- Methyl 3-(5-ethylfuran-2-carboxamido)propanoate (CAS 1248939-11-8)
- n4-(4-Chlorophenyl)-5-nitropyrimidine-4,6-diamine (CAS 103027-82-3)
- Ethylvinylbenzene (CAS 7564-63-8)
- 2-Bromo-5-cyclopropylthiazole (CAS 1159815-90-3)
- (2R)-2-amino-2-(5-isoquinolyl)ethan-1-ol (CAS 1212857-94-7)
- 2-(Cyclopropylamino)ethan-1-ol (CAS 35265-06-6)
- Cycloaspeptide D (CAS 691363-62-9)
Why CATO?
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