Tris(4-fluorophenyl)phosphine oxide CAS 18437-79-1
| CAS No. | 18437-79-1 |
| Molecular Formula | C18H12F3OP |
| Molecular Weight | 332.26 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Tris(4-fluorophenyl)phosphine oxide.
Tris(4-fluorophenyl)phosphine oxide (CAS 18437-79-1) is a high-purity analytical reference standard with the molecular formula C18H12F3OP and a molecular weight of 332.26 g/mol.
The molecular framework of Tris(4-fluorophenyl)phosphine oxide (C18H12F3OP) is characterized by a steroid core, organophosphorus functionality, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO manufactures Tris(4-fluorophenyl)phosphine oxide under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C18H12F3OP |
| Molecular Weight | 332.26 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 11.5 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1962 |
| Halogen Content | F-containing |
Related Tris Standards
- 1-(2-Fluorophenyl)-4-(trifluoromethyl)-[1,2,4]triazolo[4,3-a]quinoxaline (CAS 338962-33-7)
- 2-((4-(4-Fluorophenyl)-6-(trifluoromethyl)pyrimidin-2-yl)thio)acetic acid (CAS 505049-36-5)
- (5-(2-Fluorophenyl)isoxazol-3-yl)methyl 2-(2,5-dioxopyrrolidin-1-yl)acetate (CAS 1203419-71-9)
- 3-(4-Fluorophenyl)-5-((phenylselanyl)methyl)isoxazole (CAS 833462-34-3)
- [1-(4-Fluorophenyl)-1H-pyrazol-4-yl](1-hydroxy-2-naphthyl)methanone (CAS 956961-82-3)
- Ethyl 2-(7-(3-fluorophenyl)-4-oxothieno[3,2-d]pyrimidin-3(4H)-yl)acetate (CAS 1207032-75-4)
- 2-((4-Fluorophenyl)thio)-N-((5-(furan-2-yl)isoxazol-3-yl)methyl)acetamide (CAS 1210432-23-7)
- Ethyl 2-(7-(4-fluorophenyl)-4-oxothieno[3,2-d]pyrimidin-3(4H)-yl)acetate (CAS 1357900-00-5)
Recommended Standards
- 4-Bromo-N-cyclopentyl-2,6-dimethylbenzenesulfonamide (CAS 1704096-05-8)
- (2E,6E)-1-Iodo-3,7,11-trimethyldodeca-2,6,10-triene (CAS 89111-65-9)
- 1-((3-Bromo-4-methylphenyl)sulfonyl)-4-methylpiperidine (CAS 1704081-97-9)
- 1-((5-Bromo-2-methylphenyl)sulfonyl)-4-methylpiperidine (CAS 330830-29-0)
- Methyl (S)-4-((2-amino-3,3-dimethylbutanamido)methyl)benzoate (CAS 1185897-87-3)
- Vitamin B2 (CAS 83-88-5)
- 7-amino-5-(3-nitrophenyl)-2,4-dioxo-1,3,5,8-tetrahydro-8-oxaquinazoline-6-carbonitrile (CAS 94988-66-6)
- 2-(4-Bromo-3-methylbutyl)thiophene (CAS 1340169-23-4)
- cis-1-amino-3-hydroxy-3-methylcyclobutane-1-carboxylic acid hydrochloride (CAS 1909288-04-5)
- L-Alanine-3,3,3-d (CAS 284665-07-2)
- 2-Methylpyrido[2,3-b]pyrazine-3(4H)-thione (CAS 115366-84-2)
- 1-(2-Fluorophenyl)-3-(4-(4-(methylsulfonyl)phenyl)thiazol-2-yl)urea (CAS 882747-21-9)
- (9-Oxo-9H-fluoren-1-yl)boronic acid (CAS 194470-10-5)
- Vancomycin Hexapeptide (CAS 115236-65-2)
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